合作人类组织网络。最新情况。
The Cooperative Human Tissue Network. An update.
作者信息
LiVolsi V A, Clausen K P, Grizzle W, Newton W, Pretlow T G, Aamodt R
机构信息
Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia 19104.
出版信息
Cancer. 1993 Feb 15;71(4):1391-4. doi: 10.1002/1097-0142(19930215)71:4<1391::aid-cncr2820710434>3.0.co;2-x.
BACKGROUND
During the past decade, the National Cancer Institute became aware of a lack of availability of human tissues for research, especially in the fields of molecular biology, genetics, and immunology.
METHODS
In 1987, the National Cancer Institute (NCI) established the Cooperative Human Tissue Network (CHTN) by funding three institutions that had extensive experience in the procurement and distribution of tissues for research.
RESULTS
Since its inception, the CHTN has been expanded to five member institutions, with the addition of the Columbus Children's Hospital (the Pediatric Division for the procurement of pediatric tissues) and Case Western Reserve University. Each of the five divisions have established regional networks of institutions that supply tissues to the major divisions. From 1987 through 1991, the CHTN has distributed more than 29,000 human tissue samples and supplied approximately 500 researchers throughout the country.
CONCLUSIONS
This report describes the development and current status of the CHTN, a valuable resource to the research community.
背景
在过去十年中，美国国立癌症研究所意识到用于研究的人体组织供应不足，尤其是在分子生物学、遗传学和免疫学领域。
方法
1987年，美国国立癌症研究所（NCI）通过资助三个在组织采购和分配用于研究方面拥有丰富经验的机构，建立了合作人体组织网络（CHTN）。
结果
自成立以来，CHTN已扩展至五个成员机构，新增了哥伦布儿童医院（负责采购儿科组织的儿科部门）和凯斯西储大学。五个部门中的每个部门都建立了向主要部门供应组织的区域机构网络。从1987年到1991年，CHTN已分发了超过29000份人体组织样本，并为全国约500名研究人员提供了样本。
结论
本报告描述了CHTN的发展和现状，它是研究界的宝贵资源。
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