Zellweger J P
Dispensaire antituberculeux, Lausanne.
Schweiz Med Wochenschr. 1993 Feb 6;123(5):158-60.
Preventive chemotherapy with isoniazid (INH) is generally considered to be indicated in some patients with tuberculous infection who have a high risk of evolution towards disease. There are, however, some practical problems of treatment which may limit its application: correct assessment of tuberculin tests and risk factors, monitoring of treatment, patient compliance and management of possible side effects. Current treatment may not yet represent the ideal solution.
对于一些有发展为结核病高风险的结核感染患者,通常认为使用异烟肼(INH)进行预防性化疗是合适的。然而,治疗中存在一些实际问题可能会限制其应用:结核菌素试验和风险因素的正确评估、治疗监测、患者依从性以及可能副作用的管理。目前的治疗可能尚未代表理想的解决方案。