Grande L, Lacima G, Ros E, Font J, Pera C
Department of Surgery, Hospital Clinic i Provincial, University of Barcelona, Spain.
Am J Gastroenterol. 1993 Mar;88(3):378-81.
To evaluate esophageal motor function in patients with primary Sjögren's syndrome (PSS) and its relation to the presence of dysphagia, 20 outpatients, who met the four criteria for PSS proposed by Fox et al. were prospectively studied by esophageal manometry after dry or wet swallows. Dysphagia was present in 15 (75%) patients, although the presence or severity of the symptom was not related to any specific motility pattern. Moreover, this study did not show any correlation between dysphagia and degree of inflammatory infiltrate of the labial minor glands, the parotid flow rate, or the presence of autoantibodies. In conclusion, although dysphagia is a common complaint in patients with PSS, esophageal motor studies have failed to show any consistent pattern.
为评估原发性干燥综合征（PSS）患者的食管运动功能及其与吞咽困难的关系，对20例符合Fox等人提出的PSS四项标准的门诊患者，在干吞或湿吞后进行食管测压的前瞻性研究。15例（75%）患者存在吞咽困难，尽管该症状的存在或严重程度与任何特定的运动模式均无关。此外，本研究未显示吞咽困难与唇小涎腺炎症浸润程度、腮腺流速或自身抗体的存在之间存在任何相关性。总之，尽管吞咽困难是PSS患者的常见主诉，但食管运动研究未能显示出任何一致的模式。
