Barnes J C, Stanley O, Craig T M
Southwest Texas Veterinary Medical Center, Uvalde, TX 78802.
J Am Vet Med Assoc. 1993 Feb 1;202(3):416-8.
An adult long-haired domestic cat native to South Texas developed signs consistent with diffuse cutaneous leishmaniasis. Cutaneous leishmaniasis, caused by Leishmania mexicana, was initially diagnosed from lesions confined to the left ear. A radical pinnectomy was done and the cat was returned to its owner. Two years later, lesions developed at the stump, and lesions later developed on the cat's muzzle and nasal mucosa. All of the lesions contained numerous L mexicana amastigotes. Several treatment regimens were attempted, but without evidence of resolution. The cat was tested multiple times for evidence of impaired immunologic competence and was found to be normal. The cat failed to respond to Leishmania antigen given interdermally (Montenegro test) on several occasions. On one occasion, however, there was partial regression of the lesions following the Montenegro test. Cats in areas endemic for cutaneous leishmaniasis (South Texas) may serve as sentinels for the agent. The epidemiology of the infection in this area is largely unknown, as is the importance of cats in the spread of disease.
一只原产于南得克萨斯州的成年长毛家猫出现了与弥漫性皮肤利什曼病相符的症状。由墨西哥利什曼原虫引起的皮肤利什曼病最初是从局限于左耳的病变中诊断出来的。进行了根治性耳廓切除术，这只猫被归还给了它的主人。两年后，残端出现了病变，随后猫的口鼻部和鼻黏膜也出现了病变。所有病变中都含有大量的墨西哥利什曼原虫无鞭毛体。尝试了几种治疗方案，但均未见病情缓解迹象。对这只猫进行了多次检测，以寻找免疫功能受损的证据，结果发现其免疫功能正常。这只猫多次皮内注射利什曼原虫抗原（蒙氏试验）均无反应。然而，有一次在蒙氏试验后病变出现了部分消退。在皮肤利什曼病流行地区（南得克萨斯州）的猫可能是该病原体的哨兵。该地区感染的流行病学情况很大程度上未知，猫在疾病传播中的重要性也同样未知。
