Berg I, Butler A, Ellis M, Foster J
Leeds General Infirmary, Belmont Grove.
Dev Med Child Neurol. 1993 Feb;35(2):149-57. doi: 10.1111/j.1469-8749.1993.tb11616.x.
Sixty-four new cases of childhood epilepsy were randomly assigned to either carbamazepine, phenytoin or sodium valproate, and were assessed with behavioural measures before medication and after one and six months of treatment. Those treated with carbamazepine and sodium valproate had minor behavioural difficulties after a month of treatment, but these did not persist. Mothers of the epileptic children had unusually high levels of anxiety and depression two months, on average, after epilepsy was diagnosed.
64例儿童癫痫新病例被随机分配接受卡马西平、苯妥英钠或丙戊酸钠治疗，并在用药前以及治疗1个月和6个月后采用行为测量方法进行评估。接受卡马西平和丙戊酸钠治疗的患儿在治疗1个月后出现轻微行为问题，但这些问题并未持续存在。癫痫患儿的母亲在癫痫被诊断后平均两个月时焦虑和抑郁水平异常高。
