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Xanthoma disseminatum, a rare cause of diabetes insipidus.

作者信息

Odell W D, Doggett R S

机构信息

Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City 84132.

出版信息

J Clin Endocrinol Metab. 1993 Mar;76(3):777-80. doi: 10.1210/jcem.76.3.8445037.

DOI:10.1210/jcem.76.3.8445037
PMID:8445037
Abstract

A 33-yr-old male developed typical symptoms and findings of diabetes insipidus. A computed tomographic scan of the hypothalamus/pituitary was normal, and he was diagnosed as having idiopathic diabetes insipidus. At age 38 yr, he developed two 1- to 2-mm reddish papules on his skin. Biopsy revealed infiltrative histiocytes laden with lipid. Bone scans and bone x-rays showed widespread osteolytic and osteoblastic disease. The disease was diagnosed as a rare disseminated histiocytic disorder, xanthoma disseminatum. A classification of histiocytic disease is presented.

摘要

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