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Rare association of xanthoma disseminatum with skeletal involvement.

作者信息

Khandpur Sujay, Manchanda Yashpal, Sharma Vinod K, Singh Manoj K, Tandon Nikhil

机构信息

Department of Dermatology and Venereology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

出版信息

Australas J Dermatol. 2003 Aug;44(3):190-3. doi: 10.1046/j.1440-0960.2003.00676.x.

Abstract

A ten-year-old boy presented with a 2.5-year history of painful shoulder and hip joints, 1.5 years of yellow-brown papules and plaques on the face, flexures and trunk, and 6 months of polyuria and polydipsia. Skin biopsy revealed histological and immunohistochemical features typical of xanthoma disseminatum. Lytic bone lesions were seen in the femur and pelvis and sclerotic changes in the humerus on X-ray. Diabetes insipidus was also diagnosed

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