Chetan S
Dept. of Otolaryngology, Dr T.M.A. Pai Rotary Hospital (a unit of Kasturba Medical College), Bejai, Mangalore, Karnataka, India.
J Laryngol Otol. 1993 Jan;107(1):24-6. doi: 10.1017/s0022215100122030.
The inhalation of nasal snuff (powdered tobacco) is widely prevalent in the Indian sub-continent. The effect of snuff application on the nasal mucociliary clearance (NMMC) time has been suspected but not demonstrated before. In this study the saccharin test is used to demonstrate the rate of nasal mucociliary clearance among chronic snuff users. The study demonstrates the depressant action of snuff on the nasal mucociliary clearance rate. A pharmacological and pathological basis for the depressant action of snuff on the NMMC rate is hypothesised on the basis of the results obtained.
鼻烟（烟草粉末）的吸入在印度次大陆广泛流行。鼻烟使用对鼻黏膜纤毛清除（NMMC）时间的影响一直受到怀疑，但此前尚未得到证实。在本研究中，使用糖精试验来证明慢性鼻烟使用者的鼻黏膜纤毛清除率。该研究证明了鼻烟对鼻黏膜纤毛清除率的抑制作用。根据所获得的结果，推测了鼻烟对NMMC率产生抑制作用的药理学和病理学基础。
