Gloor M, Karenfeld A
Dermatologica. 1977;154(1):5-13. doi: 10.1159/000251024.
Ultraviolet (UV) light therapy was given over a period of several weeks to 19 test persons on one side of the back. The duration of the treatment was gradually increased from 30 sec to 7 min. After conclusion of the treatment quantitative lipid determination was made on both the treated and the untreated sides of the back, using the direct extraction method and the paper absorption method. The lipids obtained in this way were analysed by thin-layer chromatography. The following were the most important results: (1) The amount of skin surface lipids was significantly increased by UV irradiation. This results goth from an increase in the epidermal lipids as well as in the lipids of the sebaceous blands. (2) The percentage of free cholesterol in the skin surface lipids was significantly increased by UV irradiation. This increase is probably connected with a thickening of the stratum corneum. (3) The percentage of free fatty acids in the skin surface lipids is significantly increased by UV therapy. This shows that the living conditions of the saprophyte skin flora, which set free lipases, are improved as a result of this treatment or that this treatment leads to an increase of the activity of the bacterial lipases in the excretory ducts of the sebaceous glands.
对19名试验对象背部的一侧进行了为期数周的紫外线（UV）光疗。治疗时长从30秒逐渐增加至7分钟。治疗结束后，采用直接萃取法和纸吸收法对背部接受治疗和未接受治疗的两侧进行了定量脂质测定。通过薄层色谱法对以这种方式获得的脂质进行了分析。以下是最重要的结果：（1）紫外线照射使皮肤表面脂质的量显著增加。这是由于表皮脂质以及皮脂腺脂质增加所致。（2）紫外线照射使皮肤表面脂质中游离胆固醇的百分比显著增加。这种增加可能与角质层增厚有关。（3）紫外线疗法使皮肤表面脂质中游离脂肪酸的百分比显著增加。这表明，释放脂肪酶的腐生皮肤菌群的生存条件因这种治疗而得到改善，或者这种治疗导致皮脂腺排泄管中细菌脂肪酶的活性增加。
