Hotz J, Goebell H, Herfarth C, Probst M
Digestion. 1977;15(3):200-16. doi: 10.1159/000198004.
Three cases of benign pancreatic ascites have been added to 94 cases reviewed from the literature. Common characteristic of this syndrome were chronic alcoholism, intermittent abdominal pain, nausea, vomiting and considerable weight loss which occurred despite fluid accumulation. Markedly elevated protein and amylase levels in the ascitic fluid, hyperamylasemia and hypoalbuminemia were the major diagnostic clues as to the pancreatic origin of ascites. Predominant pathological findings were chronic pancreatitis with or without pseudocysts, pancreatic duct disruption, lesion which were considered to be the major pathogenic factor besides lymphatic obstruction by leaking pancreatic juice into the peritoneal cavity. Early laparotomy for diagnosis and treatment is essential. ERP might be of great value in diagnosis.
文献回顾的94例病例中新增了3例良性胰腺腹水病例。该综合征的共同特征为慢性酒精中毒、间歇性腹痛、恶心、呕吐以及尽管有液体蓄积但体重显著减轻。腹水蛋白和淀粉酶水平显著升高、高淀粉酶血症和低白蛋白血症是腹水源于胰腺的主要诊断线索。主要病理表现为伴有或不伴有假性囊肿的慢性胰腺炎、胰管破裂，这些病变被认为是除胰液漏入腹腔导致淋巴管阻塞外的主要致病因素。早期剖腹探查以进行诊断和治疗至关重要。内镜逆行胰胆管造影术（ERP）在诊断中可能具有重要价值。
