Kolbeinsson H, Jónsson A
Department of Psychiatry, Borgarspítalinn, Reykjavík, Iceland.
Acta Psychiatr Scand. 1993 Feb;87(2):123-7. doi: 10.1111/j.1600-0447.1993.tb03342.x.
A prospective study was carried out in a general hospital in Reykjavík to evaluate the prevalence of delirium and dementia among 331 patients 70 years and older who were admitted as an emergency to the medical department. Cognitive function was screened with Mental Status Questionnaire (MSQ) and Mini-Mental State Examination (MMSE) and diagnosed according to DSM-III-R for delirium and dementia. Other information obtained included social and demographic factors, drug consumption, the main condition underlying the delirium and outcome. Severe cognitive dysfunction was present in 32% of all acutely admitted patients 70 years and older, which were diagnosed further as delirium 14% and dementia 18%. At follow-up, concurrent dementia was found in 70% of the delirium patients. The main causes for delirium were cardiac failure 27%, stroke 22% and sepsis 16% and the mortality rate was 32% compared with 8% in dementia alone. The prognosis of patients with delirium and dementia depends on detecting these disorders, and the clinical skills of physicians working with acutely ill elderly patients can be improved by relatively simple screening questionnaires such as the MSQ and MMSE.
在雷克雅未克的一家综合医院进行了一项前瞻性研究,以评估331名70岁及以上因急诊入住内科的患者中谵妄和痴呆的患病率。使用精神状态问卷(MSQ)和简易精神状态检查表(MMSE)对认知功能进行筛查,并根据《精神疾病诊断与统计手册》第三版修订本(DSM-III-R)对谵妄和痴呆进行诊断。获得的其他信息包括社会和人口统计学因素、药物使用情况、导致谵妄的主要疾病以及转归。在所有70岁及以上的急性入院患者中,32%存在严重认知功能障碍,其中进一步诊断为谵妄的占14%,痴呆的占18%。在随访中,70%的谵妄患者同时患有痴呆。谵妄的主要病因是心力衰竭(27%)、中风(22%)和败血症(16%),死亡率为32%,而单纯痴呆患者的死亡率为8%。谵妄和痴呆患者的预后取决于能否检测到这些疾病,通过使用相对简单的筛查问卷(如MSQ和MMSE),可以提高诊治急症老年患者的医生的临床技能。