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肺部肉芽肿。卡介苗膀胱内灌注治疗浅表性膀胱癌的一种并发症。

Pulmonary granulomata. A complication of intravesical administration of bacillus Calmette-Guerin for superficial bladder carcinoma.

作者信息

Smith R L, Alexander R F, Aranda C P

机构信息

Department of Medicine, Department of Veterans Affairs Medical Center, New York, NY 10010.

出版信息

Cancer. 1993 Mar 1;71(5):1846-7. doi: 10.1002/1097-0142(19930301)71:5<1846::aid-cncr2820710521>3.0.co;2-o.

Abstract

Intravesical administration of bacillus Calmette-Guerin (BCG) is an effective treatment for superficial carcinoma of the bladder. The authors report a pulmonary complication characterized by miliary infiltration on chest roentgenogram and caseating granulomata on lung biopsy specimens. This case and three prior reports suggest that this complication may be a form of hypersensitivity rather than true BCG infection.

摘要

膀胱内灌注卡介苗(BCG)是浅表性膀胱癌的一种有效治疗方法。作者报告了一种肺部并发症,其特征为胸部X线片上的粟粒样浸润以及肺活检标本中的干酪样肉芽肿。该病例及之前的三份报告表明,这种并发症可能是一种超敏反应形式,而非真正的卡介苗感染。

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