Kristensen J K, Henriksen O
Acta Derm Venereol. 1979;59(2):145-7.
Blood flow was measured in the form of 133Xenon washout rate constants in a cutaneous vascular bed made passive by intracutaneous injection of a 133Xenon-papaverine mixture. Experiments were performed using injection volumes of 0.005, 0.02, 0.1 and 0.2 ml in 7 normals and 15 patients suffering from generalized scleroderma. Blood flow was closely related to the volume of fluid injected, probably reflecting dilution of tissues and increased diffusion distances when injection volumes were increased. When using injection volumes of 0.005 and 0.02 ml, blood flow was significantly reduced in the patients, as compared with normals, probably because of a decreased capillary density in cutaneous tissue in generalized scleroderma.
通过向皮内注射133氙-罂粟碱混合物使皮肤血管床处于被动状态，以133氙清除率常数的形式测量血流量。对7名正常人及15名全身性硬皮病患者进行了实验，注射体积分别为0.005、0.02、0.1和0.2毫升。血流量与注射液体的体积密切相关，这可能反映出当注射体积增加时组织稀释以及扩散距离增加。当注射体积为0.005和0.02毫升时，与正常人相比，患者的血流量显著降低，这可能是由于全身性硬皮病患者皮肤组织中毛细血管密度降低所致。
