Horne D S, Tomasz A
Department of Microbiology, Weber State University, Ogden, Utah 84408-2506.
J Bacteriol. 1993 Mar;175(6):1717-22. doi: 10.1128/jb.175.6.1717-1722.1993.
Streptococcus oralis ATCC 35037 took up radioactively labeled choline from growth medium. Most of the choline (80 to 90%) was incorporated into the cell wall teichoic acid, and about 10% was localized in the plasma membrane. While cells grew in choline-free medium, they did so at slow rates and produced cell walls with greatly reduced amounts of phosphate and no detectable choline. Cells grown in choline-free medium had grossly abnormal shape and size. Both biochemical and morphological abnormalities were reversible by addition of choline to the medium.
口腔链球菌ATCC 35037从生长培养基中摄取放射性标记的胆碱。大部分胆碱（80%至90%）被整合到细胞壁磷壁酸中，约10%定位于质膜。当细胞在无胆碱培养基中生长时，生长速度缓慢，产生的细胞壁中磷酸盐含量大大降低且未检测到胆碱。在无胆碱培养基中生长的细胞形状和大小严重异常。通过向培养基中添加胆碱，生化和形态异常均可逆转。
