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寒冷暴露下BALB/cLac和C57Bl/6J小鼠攻击行为、体温调节及内分泌反应的变化。

Changes in aggressive behavior, thermoregulation, and endocrine responses in BALB/cLac and C57Bl/6J mice under cold exposure.

作者信息

Moshkin M P, Potapov M A, Frolova O F, Evsikov V I

机构信息

Biological Institute, Siberian Branch of Russia's Academy of Sciences, Novosibirsk.

出版信息

Physiol Behav. 1993 Mar;53(3):535-8. doi: 10.1016/0031-9384(93)90150-e.

DOI:10.1016/0031-9384(93)90150-e
PMID:8451320
Abstract

Effect of cold exposure on aggressive behavior, on the concentrations of testosterone and glucocorticoids, as well as on the oxygen consumption at different ambient temperatures, and calorigenic effect of noradrenaline have been studied in BALB/cLac and C57Bl/6J males. Under normal temperature conditions, there have been no significant interstrain differences. After cold exposure (5 weeks at 6-8 degrees C), C57Bl/6J mice exhibited more pronounced adaptive changes in thermoregulation and endocrine status (increase of glucocorticoids and decrease of testosterone concentrations were less expressed in C57Bl/6J than in BALB/cLac). At the same time, males of this strain demonstrated more intensive aggression than BALB/cLac mice. Some relations between physiological and behavioral changes caused by cold exposure are discussed.

摘要

在BALB/cLac和C57Bl/6J雄性小鼠中,研究了冷暴露对攻击行为、睾酮和糖皮质激素浓度、不同环境温度下的耗氧量以及去甲肾上腺素的产热作用的影响。在正常温度条件下,品系间无显著差异。冷暴露(6 - 8摄氏度,持续5周)后,C57Bl/6J小鼠在体温调节和内分泌状态方面表现出更明显的适应性变化(C57Bl/6J小鼠糖皮质激素增加和睾酮浓度降低的程度低于BALB/cLac小鼠)。同时,该品系雄性小鼠表现出比BALB/cLac小鼠更强的攻击性。本文讨论了冷暴露引起的生理和行为变化之间的一些关系。

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