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透析患者的体外循环手术。

Cardiopulmonary bypass procedures in dialysis patients.

作者信息

Ko W, Kreiger K H, Isom O W

机构信息

Department of Surgery, New York Hospital-Cornell University Medical College, New York 10021.

出版信息

Ann Thorac Surg. 1993 Mar;55(3):677-84. doi: 10.1016/0003-4975(93)90275-m.

Abstract

To determine the operative outcome of chronic renal failure patients, we retrospectively reviewed twenty-five consecutive adult patients with chronic renal failure dependent on maintenance hemodialysis (21) or peritoneal dialysis (3), who underwent cardiopulmonary bypass procedures over a five-year period in our institution. The operations included isolated coronary artery bypass grafting in 16 patients; aortic valve replacement in 3; aortic valve replacement plus mitral valve replacement in 1; aortic valve replacement, mitral valve replacement, and coronary artery bypass grafting in 2; aortic valve replacement and coronary artery bypass grafting in 1, mitral valve replacement and coronary artery bypass grafting in 1, and repair of a thoracoabdominal aortic aneurysm in 1 patient. Fourteen operations were elective, and 11 were urgent or emergent. The number of patients with good (> 0.50), fair (0.30 to 0.50), and poor (< 0.30) left ventricular ejection fractions were 13, 9, and 3, respectively. There were 0, 7, 7, and 11 patients in New York Heart Association functional classification I, II, III, and IV, respectively. All patients were dialyzed within 24 hours before operation. All but 3 patients were managed by immediate postoperative peritoneal dialysis via a Technoff catheter placed intraoperatively (18 patients) or via a preexisting Technoff catheter (4 patients). This was then switched to hemodialysis when clinical conditions stabilized. Univariate analysis of 22 preoperative and intraoperative variables, followed by a multivariate analysis with a stepwise logistic regression model, was performed using the 30-day or in-hospital operative mortality as the dependent variable.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为了确定慢性肾衰竭患者的手术结果,我们回顾性研究了连续25例依赖维持性血液透析(21例)或腹膜透析(3例)的成年慢性肾衰竭患者,这些患者在我们机构的五年期间接受了体外循环手术。手术包括16例单纯冠状动脉搭桥术;3例主动脉瓣置换术;1例主动脉瓣置换加二尖瓣置换术;2例主动脉瓣置换、二尖瓣置换和冠状动脉搭桥术;1例主动脉瓣置换和冠状动脉搭桥术,1例二尖瓣置换和冠状动脉搭桥术,以及1例胸腹主动脉瘤修复术。14例手术为择期手术,11例为急诊或紧急手术。左心室射血分数良好(>0.50)、中等(0.30至0.50)和较差(<0.30)的患者数量分别为13例、9例和3例。纽约心脏协会功能分级I、II、III和IV级的患者分别为0例、7例、7例和11例。所有患者在术前24小时内进行了透析。除3例患者外,所有患者术后均通过术中放置的Technoff导管(18例患者)或预先存在的Technoff导管(4例患者)立即进行腹膜透析。当临床情况稳定后,再转为血液透析。以30天或住院手术死亡率为因变量,对22个术前和术中变量进行单因素分析,然后采用逐步逻辑回归模型进行多因素分析。(摘要截断于250字)

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