Kamat H A, Banker D D
Sir Hurkisondas Nurrotumdas Hospital, Maharashtra, India.
Natl Med J India. 1993 Jan-Feb;6(1):11-3.
Patients with sexually transmitted diseases form a particularly vulnerable group for infection with the human immunodeficiency virus (HIV-1), and serological surveillance is a sensitive tool for assessing the prevalence of this disease.
We carried out a serological survey for the detection of antibody to HIV-1 among persons belonging to various high-risk groups in Bombay from 1987 to 1989. Among these were 599 patients with various sexually transmitted diseases.
Thirty-nine patients (5.2%) were found to be HIV-1 antibody seropositive by the ELISA and Western blot tests. An increase in HIV-1 antibody seropositivity among both the male and female patients with sexually transmitted diseases was detected from 1987 to 1989 and seropositivity was maximally associated with condylomata acuminata, genital herpes and chancroid.
HIV-1 is established in this sentinel population and needs to be controlled vigorously.
性传播疾病患者是感染人类免疫缺陷病毒（HIV-1）的特别易感人群，血清学监测是评估该疾病流行情况的敏感工具。
1987年至1989年期间，我们在孟买对各类高危人群进行了血清学调查以检测HIV-1抗体。其中包括599例患有各种性传播疾病的患者。
通过酶联免疫吸附试验（ELISA）和免疫印迹试验发现39例患者（5.2%）HIV-1抗体血清学呈阳性。1987年至1989年期间，患性传播疾病的男性和女性患者中HIV-1抗体血清学阳性率均有所上升，且血清学阳性与尖锐湿疣、生殖器疱疹和软下疳密切相关。
HIV-1在这一哨点人群中已存在，需要大力加以控制。
