Nickel J C, Emerson L, Cornish J
Department of Urology, Queen's University, Kingston, Ontario, Canada.
J Urol. 1993 Apr;149(4):716-8. doi: 10.1016/s0022-5347(17)36191-8.
The thin mucus or glycosaminoglycan layer of the bladder may be implicated in the pathogenesis of interstitial cystitis. We developed a specific anti-mucus, antisera stabilization technique to study the ultrastructural morphological appearance of the layer, and have used this technique to compare the surface morphology of 10 control and 10 interstitial cystitis patients. The electron micrographs demonstrate the ultrastructural characteristics of the pathological changes seen in interstitial cystitis but they did not show any significant difference in the morphological appearance of the mucus or glycosaminoglycan layer between the 2 groups.
膀胱的薄黏液或糖胺聚糖层可能与间质性膀胱炎的发病机制有关。我们开发了一种特异性抗黏液、抗血清稳定技术来研究该层的超微结构形态，并使用该技术比较了10名对照者和10名间质性膀胱炎患者的表面形态。电子显微镜照片显示了间质性膀胱炎中所见病理变化的超微结构特征，但两组之间黏液或糖胺聚糖层的形态外观没有显示出任何显著差异。
