Wegener H C
National Veterinary Laboratory, Copenhagen, Denmark.
Zentralbl Veterinarmed B. 1993 Feb;40(1):13-20. doi: 10.1111/j.1439-0450.1993.tb00103.x.
A total of 989 isolates of S. hyicus were recovered from the skin of 103 piglets (9.6 isolates per piglet) with exudative epidermitis (EE), and phage typed. Phage patterns of 806 typable isolates (81%) could be divided into 44 distinct phage types. From 1 to 6 different phage types were found on individual piglets, with an average of 1.9 phage type per piglet. Antibiogram patterns of 384 isolates from 40 randomly selected piglets with EE showed a mean of 2.3 different antibiograms per investigated piglet, ranging from 1 to 6 antibiograms per piglet. Plasmid profiles of 248 S. hyicus isolates from 25 randomly selected piglets showed an average of 2.8 different plasmid profiles per piglet. Seven EE outbreaks in pig herds vaccinated with autogenous vaccine were investigated. In all these herds, strains recovered from the present outbreak differed by two or more type markers to the strains from the previous outbreak used for production of the autogenous vaccine. This finding suggest, that lack of protection might be due to the presence of other virulent types in the investigated herd than those used for production of autogenous vaccine.
从103头患有渗出性皮炎（EE）的仔猪皮肤中总共分离出989株猪葡萄球菌（每头仔猪分离出9.6株），并进行了噬菌体分型。806株可分型菌株（81%）的噬菌体模式可分为44种不同的噬菌体类型。在每头仔猪上发现1至6种不同的噬菌体类型，每头仔猪平均有1.9种噬菌体类型。对40头随机选择的患有EE的仔猪的384株分离株进行的抗菌谱模式显示，每头被调查仔猪平均有2.3种不同的抗菌谱，每头仔猪的抗菌谱范围为1至6种。对25头随机选择的仔猪的248株猪葡萄球菌分离株的质粒图谱显示，每头仔猪平均有2.8种不同的质粒图谱。对使用自家疫苗免疫的猪群中的7次EE疫情进行了调查。在所有这些猪群中，从当前疫情中分离出的菌株与用于生产自家疫苗的先前疫情中的菌株在两个或更多类型标记上存在差异。这一发现表明，缺乏保护可能是由于被调查猪群中存在除用于生产自家疫苗的菌株之外的其他有毒力类型。
