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镰状细胞病患者中,人细小病毒B19引起的急性脾滞留合并再生障碍危象。

Acute splenic sequestration together with aplastic crisis caused by human parvovirus B19 in patients with sickle cell disease.

作者信息

Mallouh A A, Qudah A

机构信息

Specialty Medical Services Department, Saudi Aramco Medical Services Organization, Dhahran, Saudi Arabia.

出版信息

J Pediatr. 1993 Apr;122(4):593-5. doi: 10.1016/s0022-3476(05)83542-5.

DOI:10.1016/s0022-3476(05)83542-5
PMID:8463907
Abstract

Three children with homozygous sickle cell disease, 22 months and 8 and 10 years of age, had clinical and hematologic manifestations of aplastic and splenic sequestration crisis simultaneously. They had an acute drop in hemoglobin level (16, 20, and 45 gm/L), reticulocytopenia (0.1%, 0.6%, and 0.3%), and sudden splenic enlargement. Evidence of recent parvovirus infection was demonstrated.

摘要

三名患有纯合子镰状细胞病的儿童,年龄分别为22个月、8岁和10岁,同时出现再生障碍性和脾隔离危象的临床和血液学表现。他们的血红蛋白水平急剧下降(分别为16、20和45克/升),网织红细胞减少(分别为0.1%、0.6%和0.3%),脾脏突然肿大。有证据表明近期感染了细小病毒。

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