Barton I K, Hilton P J, Taub N A, Warburton F G, Swan A V, Dwight J, Mason J C
Department of Renal Medicine, St Thomas' Hospital, London.
Q J Med. 1993 Feb;86(2):81-90.
Two hundred and fifty consecutive patients with acute renal failure treated by continuous haemofiltration on one intensive care unit (ICU) were studied prospectively to investigate the possibility of predicting outcome at the time of referral. Logistic regression analysis was used to identify important prognostic factors and the regression coefficients were used to weight a scoring system for the severity of illness of patients with acute renal failure. Overall survival was 53% with improvement over the course of the study. Multivariate analysis showed that outcome was related to age, need for artificial ventilation, use of inotropes, urine volume, serum bilirubin, arterial base deficit and serum creatinine. The scoring system based on the first five of these variables had a specificity of predicting death of 67% and a sensitivity of 76%.
对在一个重症监护病房（ICU）接受持续血液滤过治疗的250例急性肾衰竭连续患者进行了前瞻性研究，以探讨在转诊时预测预后的可能性。采用逻辑回归分析来确定重要的预后因素，并使用回归系数对急性肾衰竭患者的疾病严重程度评分系统进行加权。总体生存率为53%，在研究过程中有改善。多变量分析表明，预后与年龄、人工通气需求、血管活性药物的使用、尿量、血清胆红素、动脉碱缺失和血清肌酐有关。基于这些变量中的前五个变量的评分系统预测死亡的特异性为67%，敏感性为76%。
