Moret L, Chwalow J, Baudoin-Balleur C
INSERM, Unité 21, Villejuif.
Rev Epidemiol Sante Publique. 1993;41(1):65-71.
Research in public health has recently tended to take a more global perspective when considering the individual patient. In addition to a measure of functional status, the integration of the disease into the daily life of the individual, or his quality of life is what is being evaluated. This concept, while relatively recent (10-15 yrs), is the result, in part, of changes in the diagnosis and treatment of patients, particularly those with chronic and severe diseases. In clinical trials, what is sought is a measurement of change in the level of well being during the evolution of an illness or of the different levels that exist between two groups. The validation of a scale of this type requires both a qualitative and a quantitative phase with attention being paid to the methodological issues in scale development Specific statistical techniques are used to modify evolving versions. The adaptation of an existing scale into another language requires a rigorous qualitative phase before the quantitative phase is begun.
最近，公共卫生研究在考虑个体患者时倾向于采取更具全球性的视角。除了衡量功能状态外，还在评估疾病融入个体日常生活的情况，即其生活质量。这个概念虽然相对较新（10 - 15年），但部分是患者诊断和治疗方式变化的结果，尤其是那些患有慢性和严重疾病的患者。在临床试验中，寻求的是对疾病进展过程中幸福感水平的变化或两组之间存在的不同水平进行测量。这种类型量表的验证需要定性和定量阶段，同时要注意量表开发中的方法学问题。使用特定的统计技术来修改不断演变的版本。将现有量表改编成另一种语言需要在定量阶段开始之前进行严格的定性阶段。
