Olfson M, Klerman G L
Department of Psychiatry, Cornell University Medical College, New York, NY.
Am J Psychiatry. 1993 Apr;150(4):571-7. doi: 10.1176/ajp.150.4.571.
This study was done in an effort to determine whether there was a change over the past decade in the number and proportion of patients prescribed antidepressants by psychiatrists in private practice.
The authors analyzed data from the National Ambulatory Medical Care Survey for the years 1980, 1985, and 1989, focusing on visits by adults over the age of 18 years to physicians specializing in psychiatry and psychiatric subspecialties.
The number of visits that included prescribing an antidepressant medication grew from approximately 2.5 million in 1980 to 4.7 million in 1989, or from 17.9% to 30.4% of all office-based psychiatric visits. Fluoxetine, which first became available in 1988, accounted for 29.6% of the prescriptions for antidepressants in 1989. Increases in prescriptions for antidepressants were particularly evident for male patients, young adult patients, and patients with neurotic disorders.
There was an increase in the 1980s in the use of antidepressants in office-based psychiatric practice. The advent of new agents and the broadening of the clinical usefulness of existing agents may have contributed to this increase.
本研究旨在确定在过去十年中，私人执业精神科医生开具抗抑郁药的患者数量及比例是否发生了变化。
作者分析了1980年、1985年和1989年全国门诊医疗护理调查的数据，重点关注18岁以上成年人到精神科专科医生及精神科亚专科医生处就诊的情况。
开具抗抑郁药处方的就诊次数从1980年的约250万次增加到1989年的470万次，占所有门诊精神科就诊次数的比例从17.9%增至30.4%。1988年首次上市的氟西汀在1989年的抗抑郁药处方中占29.6%。抗抑郁药处方的增加在男性患者、年轻成年患者和神经症患者中尤为明显。
20世纪80年代，门诊精神科实践中抗抑郁药的使用有所增加。新药物的出现以及现有药物临床应用范围的扩大可能促成了这一增长。
