Sandström A, Wall S
Department of Epidemiology and Health Care Research, Umeå University, Sweden.
Acta Oncol. 1993;32(1):9-14. doi: 10.3109/02841869309083878.
This study focuses on mortality and cancer incidence among the male salaried employees at a copper smeltery in northern Sweden, where previously an increased lung cancer risk had been demonstrated among blue-collar workers, with all likelihood due to arsenic exposure. During the period 1928-1979 there has been 1,255 male salaried employees and 6,334 male blue-collar workers. Three cohorts were formed; those who had worked only as salaried employees, those who had worked only as blue-collar workers and those had worked in both job categories. The mortality among the entire group of salaried employees was comparatively lower than that of Sweden as a whole. The incidence of lung cancer was highest among those who had worked in both job categories, most of them former blue-collar workers. The trends in lung cancer incidence among the blue-collar workers along and among those who had had both types of jobs showed the same pattern, with a peak in the 1970s. The decrease in this trend started earlier among the salaried employees. When job category and employment cohort were analyzed together the highest risk was confirmed for those having been employed in both job categories.
本研究聚焦于瑞典北部一家铜冶炼厂男性 salaried 员工的死亡率和癌症发病率。此前已证实该厂蓝领工人患肺癌风险增加,极有可能是由于砷暴露所致。在 1928 年至 1979 年期间,有 1255 名男性 salaried 员工和 6334 名男性蓝领工人。形成了三个队列:仅担任 salaried 员工的人、仅担任蓝领工人的人以及曾从事过这两类工作的人。全体 salaried 员工的死亡率相对低于瑞典整体水平。肺癌发病率在曾从事过两类工作的人中最高,其中大多数是 former 蓝领工人。蓝领工人以及从事过两类工作的人当中肺癌发病率的趋势呈现相同模式,在 20 世纪 70 年代达到峰值。这种趋势的下降在 salaried 员工中开始得更早。当将工作类别和就业队列一起分析时,证实曾从事过两类工作的人风险最高。