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一名患有非热带性痉挛性四肢轻瘫患者及其无症状丈夫淋巴细胞中的人类嗜T淋巴细胞病毒1型(HTLV-1)序列

HTLV-1 sequences in lymphocytes of a patient with non-tropical spastic tetraparesis and her asymptomatic husband.

作者信息

Manca N, Gelmi M, Mattioli F, Gargiulo F, Terlenghi L, Pirali F, Turano A

机构信息

Institute of Microbiology, University of Brescia, Italy.

出版信息

New Microbiol. 1993 Jan;16(1):11-7.

PMID:8469167
Abstract

We describe a 65-year-old woman born and living in Northern Italy affected by non tropical spastic tetraparesis and her asymptomatic husband presenting HTLV-1 sequences in their lymphocytes detected by polymerase chain reaction (PCR). We discuss the significance of the case and the mechanism involved in HTLV-1 infection and the relationship with neurological disorders, stressing that this case is the first reported in Italy.

摘要

我们描述了一名65岁出生并居住在意大利北部的女性,她患有非热带性痉挛性四肢轻瘫,其无症状的丈夫通过聚合酶链反应(PCR)检测发现淋巴细胞中存在HTLV-1序列。我们讨论了该病例的意义以及HTLV-1感染所涉及的机制与神经疾病的关系,强调这是意大利首例报告的此类病例。

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