Jonas J B, Xu L
Department of Ophthalmology, University Erlangen-Nürnberg, Germany.
Am J Ophthalmol. 1993 Apr 15;115(4):501-5. doi: 10.1016/s0002-9394(14)74453-8.
Parapapillary chorioretinal atrophy has been shown to be associated with glaucomatous optic nerve damage. We sought to determine whether eyes with normal-pressure glaucoma have an unusually large parapapillary atrophy as compared to eyes with primary open-angle glaucoma. Color stereoscopic optic disk photographs of 34 patients with normal-pressure glaucoma and 283 patients with primary open-angle glaucoma were morphometrically analyzed. Both groups were matched for neuroretinal rim area and visual field loss. Severely myopic eyes were excluded. The parapapillary atrophy was differentiated into a peripheral Zone Alpha with irregular pigmentation and a central Zone Beta with visible sclera. Zones Alpha and Beta did not differ significantly between the two groups in either frequency or size. Eyes with normal-pressure glaucoma do not have an abnormally large parapapillary atrophy as compared to eyes with primary open-angle glaucoma, which is diagnostically and pathogenetically important.
视乳头旁脉络膜视网膜萎缩已被证明与青光眼性视神经损伤有关。我们试图确定与原发性开角型青光眼患者相比，正常眼压性青光眼患者的视乳头旁萎缩是否异常大。对34例正常眼压性青光眼患者和283例原发性开角型青光眼患者的彩色立体视盘照片进行形态计量分析。两组在神经视网膜边缘面积和视野缺损方面进行匹配。排除高度近视眼。视乳头旁萎缩分为色素不规则的周边α区和可见巩膜的中央β区。两组的α区和β区在频率或大小上均无显著差异。与原发性开角型青光眼患者相比，正常眼压性青光眼患者的视乳头旁萎缩并无异常增大，这在诊断和发病机制方面具有重要意义。
