Jonas J B, Xu L
Department of Ophthalmology, University Erlangen-Nürnberg, Germany.
Invest Ophthalmol Vis Sci. 1993 Jun;34(7):2260-5.
Parapapillary chorioretinal atrophy, neuroretinal rim loss, and a decrease of retinal vessel diameter have been described to occur in glaucomatous eyes. This study was conducted to evaluate the frequency and degree of these signs in nonarteritic anterior ischemic optic neuropathy (AION).
We evaluated morphometrically and compared stereo color optic disc photographs of 17 patients after AION, 184 patients with primary open-angle glaucoma, and 98 normal subjects.
The optic disc area and retinal vessel diameter were significantly smaller and the visibility of the retinal nerve fiber bundles was significantly reduced in patients after nonarteritic AION compared with that of the normal subjects. The optic disc shape, area, and form of zones alpha and beta of the parapapillary chorioretinal atrophy and the size and form of the neuroretinal rim did not differ significantly between these two groups. In the group of eyes with glaucoma, the neuroretinal rim was significantly smaller and the parapapillary chorioretinal atrophy was significantly larger than in the group of eyes with AION. Visibility of the retinal nerve fiber bundles and retinal vessel caliber did not differ statistically between the eyes with AION and those with glaucoma.
These results indicate that the parapapillary chorioretinal atrophy is not larger in eyes after nonarteritic AION compared with normal eyes. They show that the area and shape of the neuroretinal rim, as determined planimetrically, may not markedly change after nonarteritic AION. They confirm previous reports on a small optic disc size as a risk factor for nonarteritic AION. They agree with findings of a reduced retinal vessel caliber in eyes with optic nerve damage, independently of the cause.
已有描述称青光眼性眼中会出现视乳头旁脉络膜视网膜萎缩、神经视网膜边缘丢失以及视网膜血管直径减小。本研究旨在评估这些体征在非动脉炎性前部缺血性视神经病变（AION）中的发生频率和程度。
我们对17例AION患者、184例原发性开角型青光眼患者和98例正常受试者的立体彩色视盘照片进行了形态测量并比较。
与正常受试者相比，非动脉炎性AION患者的视盘面积和视网膜血管直径明显更小，视网膜神经纤维束的可见度明显降低。这两组之间视盘形状、面积、视乳头旁脉络膜视网膜萎缩的α区和β区形态以及神经视网膜边缘的大小和形态没有显著差异。在青光眼组眼中，神经视网膜边缘明显小于AION组眼中，视乳头旁脉络膜视网膜萎缩明显大于AION组眼中。AION组眼中和青光眼组眼中视网膜神经纤维束的可见度和视网膜血管管径在统计学上没有差异。
这些结果表明，与正常眼睛相比，非动脉炎性AION患者眼中的视乳头旁脉络膜视网膜萎缩并不更大。结果显示，通过平面测量确定的神经视网膜边缘的面积和形状在非动脉炎性AION后可能不会明显改变。这些结果证实了之前关于小视盘大小是非动脉炎性AION危险因素的报道。这些结果与视神经损伤的眼睛中视网膜血管管径减小的发现一致，与病因无关。
