采用一种新的免疫方法（结核菌素试验）检测HIV阳性患者的分枝杆菌感染。
Mycobacterial infection in HIV+ patients detected with a new immunological method (TB test).
作者信息
Vanacore R, Paladini A, Ceretelli S, Savalli E, Sbrana S, Falsini R, Scasso A, Ambrogi F
机构信息
Clinica Medica 1, Università di Pisa.
出版信息
Allerg Immunol (Paris). 1993 Jan;25(1):24-5.
Antibody response to antigen A60 (a mycobacterial antigen) was evaluated in ELISA in 18 HIV+ subjects with clinical and cultural evidences of mycobacterial infections, in 10 HIV+ subjects without Mycobacterial infections and in 22 healthy donors. We found higher levels of specific IgG in the HIV+ patients with Mycobacterial infections (mean 179.2 +/- 83 U) compared to the values of the donors (mean 92.5 +/- 35.5 U: p < 0.01). This test may be useful in the diagnosis of tuberculosis, but it needs clinical validation.
在酶联免疫吸附测定（ELISA）中，对18名有分枝杆菌感染临床及培养证据的HIV阳性受试者、10名无分枝杆菌感染的HIV阳性受试者以及22名健康供者评估了对抗原A60（一种分枝杆菌抗原）的抗体反应。我们发现，与供者的值（平均92.5±35.5 U：p<0.01）相比，有分枝杆菌感染的HIV阳性患者中特异性IgG水平更高（平均179.2±83 U）。该检测可能对结核病诊断有用，但需要临床验证。
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