Saçilik S C
Gazi Universitesi Tip Fakültesi, Mikrobiyoloji Anabilim Dali.
Mikrobiyol Bul. 1990 Jul;24(3):198-204.
IgG antibody titer levels against two different antigens of M tuberculosis were investigated in the sera of 40 patients with active pulmonary tuberculosis and 16 with inactive pulmonary tuberculosis and 24 healthy controls by using ELISA technique. While a sensitivity of 92% and a specificity of 88% were determined for MSO (mycobacterial sonicate antigen) antigen, a sensitivity of 79% and a specificity 73% were determined for the other PPD (Purified protein derivative) antigen. ELISA, for serodiagnosis of tuberculosis was compared in terms of sensitivity for AFB (acid fast bacilli stain) and culture methods. In this study, the sensitivity of ELISA was found as 92% for MSO antigen and 79% for PPD antigen while it was 58% for AFB method and 95% for the culture method.
采用酶联免疫吸附测定（ELISA）技术，对40例活动性肺结核患者、16例非活动性肺结核患者以及24名健康对照者血清中针对结核分枝杆菌两种不同抗原的IgG抗体滴度水平进行了研究。对于分枝杆菌超声处理抗原（MSO），测定的敏感性为92%，特异性为88%；对于另一种纯化蛋白衍生物（PPD）抗原，测定的敏感性为79%，特异性为73%。就抗酸杆菌（AFB）染色和培养方法的敏感性而言，对用于结核病血清学诊断的ELISA进行了比较。在本研究中，ELISA对MSO抗原的敏感性为92%，对PPD抗原的敏感性为79%，而AFB方法的敏感性为58%，培养方法的敏感性为95%。
