从含有乙酰水杨酸和可待因的非处方药中分离出可待因的滥用情况。

Abuse of codeine separated from over-the-counter drugs containing acetylsalicylic acid and codeine.

作者信息

Jensen S, Hansen A C

机构信息

Department of Forensic Pathology, Aarhus University, Risskov, Denmark.

出版信息

Int J Legal Med. 1993;105(5):279-81. doi: 10.1007/BF01370385.

DOI:10.1007/BF01370385

PMID:8471545

Abstract

In Denmark a new trend concerning the abuse of codeine has been observed. Danish drug abusers have discovered that codeine is easily separated from certain drugs containing acetylsalicylic acid and codeine. When separated the codeine can be used either orally or intravenously. Three different drugs combining acetylsalicylic acid and codeine are available in Denmark, but codeine is only easily separable from one of these. Applying the same procedure to the two other drugs produces unpredictable or unfavourable ratios of codeine to acetylsalicylic acid. In several countries, however, similar drugs combining acetylsalicylic acid and codeine are available. It is not possible from a list of constituents to predict how easily codeine can be separated from a particular drug. Therefore it is strongly recommended that relevant drugs are tested at local forensic laboratories. In case codeine is found to be very easily separated from a product appropriate action should be taken.

摘要

在丹麦，已观察到有关可待因滥用的一种新趋势。丹麦的药物滥用者发现，可待因很容易从某些含有乙酰水杨酸和可待因的药物中分离出来。分离出来后，可待因既可以口服，也可以静脉注射。丹麦有三种不同的将乙酰水杨酸和可待因结合在一起的药物，但可待因仅能很容易地从其中一种中分离出来。对另外两种药物采用相同的程序会产生不可预测或不理想的可待因与乙酰水杨酸的比例。然而，在几个国家，也有类似的将乙酰水杨酸和可待因结合在一起的药物。从成分清单中无法预测可待因从特定药物中分离的难易程度。因此，强烈建议在当地法医实验室对相关药物进行检测。如果发现可待因很容易从某种产品中分离出来，就应采取适当行动。