Battaglia M, Ferini-Strambi L, Smirne S, Bernardeschi L, Bellodi L
Department of Neuropsychiatric Sciences, University of Milan School of Medicine, S. Raffaele Hospital, Italy.
Biol Psychiatry. 1993 Mar 1;33(5):326-34. doi: 10.1016/0006-3223(93)90321-4.
The sleep parameters of never-depressed borderline subjects and age- and sex-matched normal controls were compared by continuous 48-hr ambulatory electroencephalographic (EEG) monitoring. Borderline subjects had a significantly shorter rapid eye movement latency, normal architecture of rapid eye movements sleep, and had familial risks for mood disorders four times greater than in the families of controls. Reduced latency of rapid eye movement can be a trait indicator of liability to depression, present before the clinical appearance of the disorder, and demonstrable in a putative high-risk population.
通过连续48小时动态脑电图（EEG）监测，比较了从未患过抑郁症的边缘型人格障碍患者与年龄和性别匹配的正常对照组的睡眠参数。边缘型人格障碍患者的快速眼动潜伏期显著缩短，快速眼动睡眠结构正常，且其家族患情绪障碍的风险是对照组家族的四倍。快速眼动潜伏期缩短可能是抑郁症易感性的一个特质指标，在该疾病临床出现之前就已存在，并且在假定的高危人群中可以得到证实。
