Oster O
Institut für Klinische Chemie und Laboratoriumsmedizin, Universitätsklinik Mainz, Germany.
Clin Chim Acta. 1993 Feb 28;214(2):209-18. doi: 10.1016/0009-8981(93)90112-h.
The trace element concentrations (Cu, Zn, Fe) in sera from patients with dilated cardiomyopathy are reported. Patients with dilated cardiomyopathy have high copper and low zinc concentrations in serum compared to healthy controls. The trace element concentration profile is different from that of other heart diseases like myocardial infarction and coronary heart disease. The copper concentration in serum shows a highly significant inverse relationship with the ejection fraction and the cardiac index. Pathophysiological processes which raise the copper concentration in serum may influence the ejection fraction and the cardiac index.
报告了扩张型心肌病患者血清中的微量元素浓度（铜、锌、铁）。与健康对照组相比，扩张型心肌病患者血清中的铜浓度较高，锌浓度较低。这种微量元素浓度分布与心肌梗死和冠心病等其他心脏病不同。血清中的铜浓度与射血分数和心脏指数呈高度显著的负相关。血清中铜浓度升高的病理生理过程可能会影响射血分数和心脏指数。
