Kennedy F M, Astbury J, Needham J R, Cheasty T
Health and Safety Executive, Belford House, Edinburgh.
Epidemiol Infect. 1993 Apr;110(2):247-51. doi: 10.1017/s0950268800068163.
A small cluster of dysenteric illness, due to Shigella flexneri, was identified among technical assistants of a primate research unit. All of the affected individuals had been in regular contact with a colony of cynomolgus macaque monkeys, one of which was known to have suffered from acute haemorrhagic colitis in the preceding few weeks. Four monkeys were found to be excreting S. flexneri bacilli of identical antigen type (1b) to that isolated from the human cases. Investigation of working practices revealed the potential for inadvertent faeco-oral spread and the need to improve existing control methods. We conclude that this small outbreak of shigellosis represents a primate-associated occupational zoonosis. The risk may not be fully appreciated by handlers or their doctors.
在一个灵长类动物研究单位的技术人员中，发现了一小群由福氏志贺菌引起的痢疾性疾病。所有受影响的个体都曾与一群食蟹猕猴有过定期接触，其中一只猕猴在之前几周被确诊患有急性出血性结肠炎。发现四只猴子排出的福氏志贺菌菌株与从人类病例中分离出的菌株具有相同的抗原类型（1b）。对工作流程的调查揭示了粪便-口传播的潜在风险以及改进现有控制方法的必要性。我们得出结论，这次小规模的志贺菌病暴发是一种与灵长类动物相关的职业性人兽共患病。动物饲养者或他们的医生可能并未充分意识到这种风险。
