Kanal E, Gillen J, Evans J A, Savitz D A, Shellock F G
Department of Radiology, University of Pittsburgh, PA 15213.
Radiology. 1993 May;187(2):395-9. doi: 10.1148/radiology.187.2.8475280.
Epidemiologic data were obtained to evaluate potential risks from exposure to the static and time-varying magnetic fields used in magnetic resonance (MR) imaging. A questionnaire sent to women workers in more than 90% of clinical MR facilities in the United States addressed menstrual-reproductive experiences, work activities, and potential confounders (eg, age, smoking, alcohol use). In 1,915 completed questionnaires, 1,421 pregnancies were reported: 280 occurred in an MR worker (technologist or nurse), 894 in an employee in another job, 54 in a student, and 193 in homemakers. Comparing MR-worker pregnancies with those occurring in employees at other jobs, a relative risk ratio of 1.27 (95% confidence interval [CI], 0.92-1.77) was found for spontaneous abortions; for conception taking more than 12 months, 0.90 (CI, 0.54-1.51); for delivery before 39 weeks, 1.19 (CI, 0.76-1.88); for birth weight below 5.5 lb (2.5 kg), 1.01 (CI, 0.50-2.04); and for male gender of the offspring, 0.99 (CI, 0.80-1.22). Adjustment for maternal age, smoking, and alcohol use also failed to markedly change any of the associations. These results suggest that there is not a substantial increase in these common adverse reproductive outcomes.
获取了流行病学数据,以评估磁共振成像(MR)中使用的静态和随时间变化的磁场暴露带来的潜在风险。向美国90%以上临床MR设施中的女工发放了一份问卷,内容涉及月经生殖经历、工作活动和潜在混杂因素(如年龄、吸烟、饮酒)。在1915份完整问卷中,报告了1421次怀孕:280次发生在MR工作人员(技术人员或护士)身上,894次发生在从事其他工作的员工身上,54次发生在学生身上,193次发生在家庭主妇身上。将MR工作人员的怀孕情况与从事其他工作的员工的怀孕情况进行比较,发现自然流产的相对风险比为1.27(95%置信区间[CI],0.92 - 1.77);受孕超过12个月的相对风险比为0.90(CI,0.54 - 1.51);39周前分娩的相对风险比为1.19(CI,0.76 - 1.88);出生体重低于5.5磅(2.5千克)的相对风险比为1.01(CI,0.50 - 2.04);后代为男性性别的相对风险比为0.99(CI,0.80 - 1.22)。对产妇年龄、吸烟和饮酒进行调整后,也未能显著改变任何关联。这些结果表明,这些常见的不良生殖结局没有大幅增加。