Christoffersen T, Fors T, Ringberg U, Holtedahl K
Department of Ophthalmology, University of Tromsø, Norway.
Acta Ophthalmol (Copenh). 1993 Feb;71(1):103-8. doi: 10.1111/j.1755-3768.1993.tb04970.x.
Intraocular pressure was measured in 132 consecutive patients over the age of 20 in a general practice with two general practitioners (GP). Tono-Pen tonometry was compared to Goldmann applantation tonometry in a masked, randomized design. Also, agreement between Tono-Pen measurements by the GPs and the ophthalmologist was estimated. Both mean difference between Tono-Pen and Goldmann applantation measurements and mean differences between Tono-Pen readings made by GPs and ophthalmologist were less than 1 mmHg. Ninety-five percent limits of agreement between the two methods were approximately -4.5 mmHg and 5.5 mmHg, and between observers approximately -4 mmHg and 5 mmHg. The Tono-Pen was agreeable both to patients and physicians. The GPs made as accurate measurements as the ophthalmologist. The wide limits of agreement are clinically much more important than the small differences between means. Random variation was much greater than systematic variation. Wide limits of agreement will apply to all known methods of clinical tonometry.
在一家普通诊所，由两名全科医生（GP）对132名年龄超过20岁的连续患者进行了眼压测量。采用双盲随机设计，将Tono-Pen眼压计测量结果与Goldmann压平眼压计测量结果进行比较。此外，还评估了全科医生和眼科医生使用Tono-Pen测量结果之间的一致性。Tono-Pen测量结果与Goldmann压平眼压计测量结果之间的平均差异，以及全科医生和眼科医生使用Tono-Pen测量结果之间的平均差异均小于1 mmHg。两种方法之间95%的一致性界限约为-4.5 mmHg至5.5 mmHg，观察者之间约为-4 mmHg至5 mmHg。Tono-Pen眼压计受到患者和医生的认可。全科医生测量的准确性与眼科医生相当。一致性界限较宽在临床上比平均值之间的微小差异更为重要。随机变异远大于系统变异。较宽的一致性界限适用于所有已知的临床眼压测量方法。
