通过聚（L-赖氨酸）偶联和脂质体包封递送反义寡核苷酸。 - Suppr

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超能文献

Delivery of antisense oligonucleotides by poly(L-lysine) conjugation and liposome encapsulation.

作者信息

Clarenc J P, Degols G, Leonetti J P, Milhaud P, Lebleu B

机构信息

UA CNRS 1191 Génétique Moléculaire, Université Montpellier II Sciences et Techniques du Languedoc, France.

出版信息

Anticancer Drug Des. 1993 Feb;8(1):81-94.

PMID:8476504

Abstract

摘要

相似文献

Delivery of antisense oligonucleotides by poly(L-lysine) conjugation and liposome encapsulation.通过聚（L-赖氨酸）偶联和脂质体包封递送反义寡核苷酸。

Anticancer Drug Des. 1993 Feb;8(1):81-94.

"Smart" delivery of antisense oligonucleotides by anionic pH-sensitive liposomes.阴离子pH敏感脂质体介导反义寡核苷酸的“智能”递送

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Requirements for delivery of active antisense oligonucleotides into cells with lipid carriers.

Methods Enzymol. 2004;387:210-30. doi: 10.1016/S0076-6879(04)87013-7.

Liposomes as a drug delivery system for antisense oligonucleotides.脂质体作为反义寡核苷酸的药物递送系统。

Antisense Res Dev. 1992 Summer;2(2):165-76. doi: 10.1089/ard.1992.2.165.

Inhibition of Epstein Barr Virus LMP1 gene expression in B lymphocytes by antisense oligonucleotides: uptake and efficacy of lipid-based and receptor-mediated delivery systems.反义寡核苷酸对B淋巴细胞中爱泼斯坦-巴尔病毒LMP1基因表达的抑制作用：基于脂质和受体介导的递送系统的摄取及效果

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Covalent protein-oligonucleotide conjugates for efficient delivery of antisense molecules.

Bioconjug Chem. 1997 Nov-Dec;8(6):935-40. doi: 10.1021/bc970172u.

In vitro delivery of antisense oligonucleotides.

Cell Mol Biol Lett. 2002;7(2):236-7.

Receptor-mediated oligodeoxynucleotides delivery by estradiol and folic acid polylysine conjugates.通过雌二醇和叶酸多聚赖氨酸缀合物进行受体介导的寡脱氧核苷酸递送。

Cytotechnology. 1993;11 Suppl 1:S30-4.

Folic acid-polylysine carrier improves efficacy of c-myc antisense oligodeoxynucleotides on human melanoma (M14) cells.叶酸-聚赖氨酸载体提高c-myc反义寡脱氧核苷酸对人黑色素瘤（M14）细胞的疗效。

Anticancer Res. 1997 Jan-Feb;17(1A):29-35.

Cationic liposome-encapsulated antisense oligonucleotide mediates efficient killing of intracellular Leishmania.阳离子脂质体包裹的反义寡核苷酸介导对细胞内利什曼原虫的有效杀伤。

Biochem J. 1999 Jun 1;340 ( Pt 2)(Pt 2):393-6.

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Investigation of PLGA nanoparticles in conjunction with nuclear localization sequence for enhanced delivery of antimiR phosphorothioates in cancer cells in vitro.PLGA 纳米粒与核定位序列联合用于增强反义 miR 硫代磷酸酯在体外癌细胞中的递送

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Nanomedicines based on recombinant fusion proteins for targeting therapeutic siRNA oligonucleotides.基于重组融合蛋白的纳米药物用于靶向治疗性小干扰RNA寡核苷酸。

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The use of synthetic polymers for delivery of therapeutic antisense oligodeoxynucleotides.合成聚合物用于递送治疗性反义寡脱氧核苷酸。

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The spherulites(TM): a promising carrier for oligonucleotide delivery.球晶（TM）：一种有前景的寡核苷酸递送载体。

Nucleic Acids Res. 2000 Aug 15;28(16):3134-42. doi: 10.1093/nar/28.16.3134.

Inhibition of luciferase expression by synthetic hammerhead ribozymes and their cellular uptake.合成锤头状核酶对荧光素酶表达的抑制作用及其细胞摄取

Nucleic Acids Res. 1999 Aug 1;27(15):3159-67. doi: 10.1093/nar/27.15.3159.

Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells.选择最佳寡核苷酸组成以在链球菌溶血素O介导的递送至人白血病细胞后实现最大反义效应。

Nucleic Acids Res. 1998 Apr 1;26(7):1567-75. doi: 10.1093/nar/26.7.1567.

Application of antisense DNA method for the study of molecular bases of brain function and behavior.反义DNA方法在脑功能和行为分子基础研究中的应用。

Behav Genet. 1996 May;26(3):279-92. doi: 10.1007/BF02359384.

Antisense oncogene and tumor suppressor gene therapy of cancer.癌症的反义癌基因与肿瘤抑制基因治疗

J Mol Med (Berl). 1996 Apr;74(4):191-204. doi: 10.1007/BF00204749.

Facilitating oligonucleotide delivery: helping antisense deliver on its promise.促进寡核苷酸递送：助力反义技术兑现承诺。

Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3161-3. doi: 10.1073/pnas.93.8.3161.

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