Barbucci R, Magnani A, Baszkin A, Da Costa M L, Bauser H, Hellwig G, Martuscelli E, Cimmino S
C.R.I.S.M.A., University of Siena, Italy.
J Biomater Sci Polym Ed. 1993;4(3):245-73. doi: 10.1163/156856293x00555.
Three hyaluronic acid derivatives with different types and/or percentages of esterification, were analyzed by means of static contact angle measurements, SEM, ESCA, ATR/FT-IR, WAXS, DSC and TGA. The physico-chemical characterization of the three different samples, in both dry and wet state, was provided in terms of surface and bulk properties. ESCA and infrared analyses showed that the surface composition of all samples differs from that of the bulk. The hydrophilic-hydrophobic character of the samples changed according to the chemical composition as shown by ESCA and contact angle measurements. Both infrared and contact angle measurements reveal that surface restructuring occurred upon hydration for all the samples and the greater the hydrophilic character of the sample, the greater and faster the restructuring phenomenon. A clear picture of the different types of chemical groups has been established at different depth for the three materials.
通过静态接触角测量、扫描电子显微镜（SEM）、电子能谱化学分析（ESCA）、衰减全反射傅里叶变换红外光谱（ATR/FT-IR）、广角X射线散射（WAXS）、差示扫描量热法（DSC）和热重分析法（TGA），对三种具有不同酯化类型和/或酯化百分比的透明质酸衍生物进行了分析。从表面和本体性质方面，给出了三种不同样品在干燥和湿润状态下的物理化学特性。ESCA和红外分析表明，所有样品的表面组成均与本体不同。如ESCA和接触角测量所示，样品的亲水-疏水特性随化学组成而变化。红外和接触角测量均表明，所有样品在水合时都会发生表面重构，且样品的亲水性越强，重构现象越显著、速度越快。已明确三种材料在不同深度处不同类型化学基团的情况。
