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Antigenic analysis of the major outer membrane protein of Haemophilus somnus with monoclonal antibodies.

作者信息

Tagawa Y, Haritani M, Ishikawa H, Yuasa N

机构信息

National Institute of Animal Health, Ibaraki, Japan.

出版信息

Infect Immun. 1993 May;61(5):2257-9. doi: 10.1128/iai.61.5.2257-2259.1993.

DOI:10.1128/iai.61.5.2257-2259.1993
PMID:8478121
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC280836/
Abstract

The major outer membrane protein of Haemophilus somnus possesses at least five distinct epitopes. Three surface-exposed epitopes on the major outer membrane protein include a conserved epitope with potential for development of a vaccine and a diagnostic test and two variable epitopes responsible for antigenic differences among strains; the remaining two epitopes are well preserved among strains but not exposed on the cell surface.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7d/280836/ddbe4e204a39/iai00017-0675-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7d/280836/3d567bf8795f/iai00017-0674-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7d/280836/37d8ce3d0d73/iai00017-0674-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7d/280836/ddbe4e204a39/iai00017-0675-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7d/280836/3d567bf8795f/iai00017-0674-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7d/280836/37d8ce3d0d73/iai00017-0674-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7d/280836/ddbe4e204a39/iai00017-0675-a.jpg

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本文引用的文献

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2
Purification and partial characterization of the major outer membrane protein of Haemophilus somnus.睡眠嗜血杆菌主要外膜蛋白的纯化及部分特性分析
Infect Immun. 1993 Jan;61(1):91-6. doi: 10.1128/iai.61.1.91-96.1993.
3
Purification and comparison of outer membrane protein P2 from Haemophilus influenzae type b isolates.b型流感嗜血杆菌分离株外膜蛋白P2的纯化及比较
通过主要外膜蛋白基因测序和脉冲场凝胶电泳确定的主要克隆性血栓栓塞性脑膜脑炎组
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Infect Immun. 1993 Oct;61(10):4153-7. doi: 10.1128/iai.61.10.4153-4157.1993.
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Monoclonal antibodies directed against a cell surface-exposed outer membrane protein of Haemophilus influenzae type b.针对b型流感嗜血杆菌细胞表面暴露的外膜蛋白的单克隆抗体。
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Cleavage of structural proteins during the assembly of the head of bacteriophage T4.在噬菌体T4头部组装过程中结构蛋白的切割
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Antigenic specificity of convalescent serum from cattle with haemophilus somnus-induced experimental abortion.来自因睡眠嗜血杆菌诱导实验性流产的牛的恢复期血清的抗原特异性。
Infect Immun. 1987 Jun;55(6):1381-6. doi: 10.1128/iai.55.6.1381-1386.1987.
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Purification and analysis with monoclonal antibodies of P2, the major outer membrane protein of nontypable Haemophilus influenzae.不可分型流感嗜血杆菌主要外膜蛋白P2的单克隆抗体纯化及分析
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