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[光变应性:皮肤科患者光斑贴试验结果(作者译)]

[Photoallergy: results of photo patch testing in dermatological patients (author's transl)].

作者信息

Mischer P

出版信息

Wien Klin Wochenschr. 1977 Mar 18;89(6):185-92.

PMID:848027
Abstract

150 patients with light sensitivity of unknown aetiology were photo patch tested at the 2nd Department of Dermatology University of Vienna. 22 patients showed photoallergy. The identified photoallergens were mostly halogenated salicylanilides and other phenolic compounds. These substances are used as antimicrobials in soaps and cosmetics and as antimycotics in dermatological preparations. Four of the patients showed allergic contact photosensitivity to chlorpromazine. In two patients a new photoallergen has, perhaps, been discovered, namely a derivative of phthalic acid which is employed as fungicidal pesticide. The problems and consequences of photoallergy are discussed.

摘要

150例病因不明的光敏感患者在维也纳大学第二皮肤科接受了光斑贴试验。22例患者表现为光过敏。所鉴定出的光变应原大多为卤化水杨酰苯胺和其他酚类化合物。这些物质在肥皂和化妆品中用作抗菌剂,在皮肤科制剂中用作抗真菌剂。4例患者对氯丙嗪表现出过敏性接触性光敏感。在2例患者中,可能发现了一种新的光变应原,即用作杀真菌农药的邻苯二甲酸衍生物。文中讨论了光过敏的问题及后果。

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