氟烷剂量对纹状体多巴胺的影响：一项体内微透析研究。
The effect of halothane dose on striatal dopamine: an in vivo microdialysis study.
作者信息
Miyano K, Tanifuji Y, Eger E I
机构信息
Department of Anesthesiology, Jikei University School of Medicine, Tokyo, Japan.
出版信息
Brain Res. 1993 Mar 12;605(2):342-4. doi: 10.1016/0006-8993(93)91763-i.
PMID:8481785
Abstract
The relationship between a level of an anesthesia state and striatal dopamine concentration was investigated. The effect of halothane administration on dopamine level in rat striatal extracellular fluid was determined in tracheotomized rats, using an in vivo brain microdialysis method. The striatal dopamine was increased by halothane doses. The correlation coefficient between halothane and dopamine concentrations was 0.69.
摘要
研究了麻醉状态水平与纹状体多巴胺浓度之间的关系。采用体内脑微透析法，在气管切开的大鼠中测定了氟烷给药对大鼠纹状体细胞外液中多巴胺水平的影响。氟烷剂量增加时，纹状体多巴胺含量升高。氟烷与多巴胺浓度之间的相关系数为0.69。
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