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荧光素在检测外淋巴瘘中的应用:猫的研究

Fluorescein use in the detection of perilymphatic fistula: a study in cats.

作者信息

Bojrab D I, Bhansali S A

机构信息

EAR Consultants of Michigan, Southfield.

出版信息

Otolaryngol Head Neck Surg. 1993 Apr;108(4):348-55. doi: 10.1177/019459989310800407.

DOI:10.1177/019459989310800407
PMID:8483606
Abstract

A stained or colored perilymph would be a valuable tool to otologists for the detection of a perilymph fistula. We studied the effect of intravenously injected fluorescein on the inner ear in seven cats. Still and video photography was used to clearly document our findings. Intravenously injected fluorescein appeared within the soft tissue in less than 1 minute and stayed there for at least 3 1/2 hours. Fluorescence around the round window niche resulted from soft tissue (mucosal) fluorescence and extravasation of interstitial fluid (transudate). No fluorescence of perilymph was detected. Because of this, we do not believe intravenously injected fluorescein is useful in the detection of perilymph fistula. Intrathecal injection caused quick and intense staining of labyrinthine fluid.

摘要

染色或带色的外淋巴对于耳科医生检测外淋巴瘘来说是一种很有价值的工具。我们研究了静脉注射荧光素对7只猫内耳的影响。使用静态和视频摄影来清晰记录我们的发现。静脉注射的荧光素在不到1分钟内出现在软组织中,并在那里停留至少3个半小时。圆窗龛周围的荧光是由软组织(黏膜)荧光和间质液(漏出液)外渗引起的。未检测到外淋巴有荧光。因此,我们认为静脉注射荧光素在检测外淋巴瘘方面并无用处。鞘内注射导致迷路液迅速且强烈地染色。

相似文献

1
Fluorescein use in the detection of perilymphatic fistula: a study in cats.荧光素在检测外淋巴瘘中的应用:猫的研究
Otolaryngol Head Neck Surg. 1993 Apr;108(4):348-55. doi: 10.1177/019459989310800407.
2
Intravenous fluorescein for detection of perilymphatic fistulas.
Am J Otol. 1993 Jan;14(1):51-5.
3
Intraoperative assessment of perilymphatic fistulas with intrathecal administration of fluorescein.术中通过鞘内注射荧光素评估外淋巴瘘。
Laryngoscope. 2002 Sep;112(9):1614-8. doi: 10.1097/00005537-200209000-00016.
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Rapid protein test for perilymph fistula.用于检测外淋巴瘘的快速蛋白质检测
Otolaryngol Head Neck Surg. 1991 Sep;105(3):422-6. doi: 10.1177/019459989110500313.
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[Perilymph fistula: diagnosis by detection of perilymph in the middle ear by beta-2 transferrin immunofixation].[外淋巴瘘:通过β-2转铁蛋白免疫固定法检测中耳内的外淋巴进行诊断]
Ann Otolaryngol Chir Cervicofac. 1994;111(4):180-4.
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Chronic perilymphatic fistula: experimental model in the guinea pig.慢性外淋巴瘘:豚鼠实验模型
Otolaryngol Head Neck Surg. 1988 Oct;99(4):380-8. doi: 10.1177/019459988809900405.
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Fluorescein as an easy, low-cost, indirect, or reverse intraoperative marker to rule out perilymph versus local injection.
Am J Otol. 1996 Mar;17(2):259-62.
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Magnetic resonance imaging of perilymphatic fistula.外淋巴瘘的磁共振成像
Laryngoscope. 1993 Jul;103(7):729-33. doi: 10.1288/00005537-199307000-00004.
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Vestibular effects of chronic perilymph fistula in the cat.猫慢性外淋巴瘘的前庭效应
Otolaryngol Head Neck Surg. 1990 Jun;102(6):701-8. doi: 10.1177/019459989010200613.
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[Topography of the round window and its significance for the surgical therapy of perilymph fistulas].[圆窗的局部解剖及其在外淋巴瘘手术治疗中的意义]
Laryngol Rhinol Otol (Stuttg). 1988 Jan;67(1):28-30.

引用本文的文献

1
Perilymph fistula: fifty years of controversy.外淋巴瘘:五十年的争议
ISRN Otolaryngol. 2012 Jul 31;2012:281248. doi: 10.5402/2012/281248. Print 2012.
2
[Fluorescence of the middle ear].[中耳的荧光]
HNO. 2008 Feb;56(2):239-47. doi: 10.1007/s00106-007-1667-9.