Abolnik I Z, Lossos I S, Gillis D, Breuer R
Internal Medicine Department, Methodist Hospital Central, Methodist Hospitals of Memphis, Tennessee.
Am J Med Sci. 1993 May;305(5):297-303. doi: 10.1097/00000441-199305000-00006.
To determine the risk factors, clinical presentation, and long-term outcome of primary spontaneous pneumothorax (PSP), all available cases of PSP in the Israeli Defense Forces (IDF) were retrospectively reviewed. Using the computerized IDF database, all men who had pneumothorax were identified and a telephone interview obtained with 343 individuals, 286 of whom had PSP and agreed to participate in this study. These 286 persons experienced 498 episodes of PSP, with 314 medical records available for review. Average length of follow-up from the first episode of PSP was 107.2 months. Of the study population, 11.5% had a positive family history for PSP. The height-to-weight ratio was significantly and positively correlated with the number of PSP episodes per person, with the regression coefficient being 0.49. The age distribution of those with PSP had a monophasic pattern, with the average age being 25.3 years on first episode. More than one episode of PSP occurred in 41.3% of patients. No ipsilateral recurrences were observed after surgery. Treatment with a sclerosing agent seemed to be more effective in preventing ipsilateral recurrences of PSP than chest tube insertion alone (26.5% vs. 38.3%). Primary spontaneous pneumothorax is an important medical problem, especially in men of military age. It has a significant inherited component in its etiology, with asthenic body build being an additional risk factor. Based on a literature review and the data obtained from this study, it was concluded that chest tube insertion with intrapleural instillation of a sclerosing agent is the preferred nonsurgical invasive treatment modality in PSP.
为了确定原发性自发性气胸(PSP)的危险因素、临床表现及长期预后,我们对以色列国防军(IDF)中所有PSP病例进行了回顾性研究。利用IDF的计算机数据库,识别出所有气胸患者,并对343名个体进行了电话访谈,其中286人患有PSP并同意参与本研究。这286人共经历了498次PSP发作,有314份病历可供查阅。从首次PSP发作开始的平均随访时间为107.2个月。在研究人群中,11.5%有PSP家族史阳性。身高体重比与每人PSP发作次数呈显著正相关,回归系数为0.49。PSP患者的年龄分布呈单峰模式,首次发作时的平均年龄为25.3岁。41.3%的患者发生过不止一次PSP发作。手术后未观察到同侧复发。与单纯胸腔闭式引流相比,使用硬化剂治疗似乎更能有效预防PSP同侧复发(26.5%对38.3%)。原发性自发性气胸是一个重要的医学问题,尤其是在军事年龄的男性中。其病因有显著的遗传因素,身体虚弱也是一个额外的危险因素。基于文献综述和本研究获得的数据,得出结论:胸腔闭式引流并胸膜腔内注入硬化剂是PSP首选的非手术侵入性治疗方式。