Chen Y M, Lu C C, Perng R P
Chest Department, Veterans General Hospital-Taipei, Shih-pai, Taiwan, ROC.
Am Rev Respir Dis. 1993 May;147(5):1299-302. doi: 10.1164/ajrccm/147.5.1299.
Silicone fluid injection for mammary augmentation is a well-known illegal procedure. It has been associated with many complications, including local tissue granulomatous reaction, chronic infection, and sclerosis, but pulmonary involvement in human beings has been documented in only six cases. We describe three more such cases of pulmonary embolism. These three patients were all female, young, and previously healthy. They received the procedures only for cosmetic reasons. Unfortunately, one of them died and another lived with the sequelae of pulmonary fibrosis. The mortality rate of the nine total patients with pulmonary embolism induced by silicone fluid, including our three cases, is 33%. Because of this high mortality rate and long-term sequelae of pulmonary fibrosis, no silicone fluid injection should be given for cosmetic reasons, especially in mammary augmentation in which a large volume of silicone fluid is more likely to be used, and the early use of corticosteroid therapy may be helpful.
注射硅胶液隆乳是一种众所周知的非法手术。它与许多并发症有关，包括局部组织肉芽肿反应、慢性感染和硬化，但人类肺部受累仅记录了6例。我们描述另外3例这样的肺栓塞病例。这3例患者均为年轻女性，既往健康。她们接受手术仅出于美容目的。不幸的是，其中1例死亡，另1例留有肺纤维化后遗症。包括我们的3例在内，硅胶液所致肺栓塞的9例患者总死亡率为33%。鉴于这种高死亡率和肺纤维化的长期后遗症，不应出于美容目的进行硅胶液注射，尤其是在隆乳手术中，因为更可能使用大量硅胶液，早期使用皮质类固醇治疗可能会有帮助。
