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心肌抗肌凝蛋白闪烁扫描术的新应用：多肌炎中心肌疾病的诊断

New application of myocardial antimyosin scintigraphy: diagnosis of myocardial disease in polymyositis.

作者信息

Le Guludec D, Lhote F, Weinmann P, Royer I, Jarrousse B, Caillat-Vigneron N, Guillevin L, Moretti J L

机构信息

Service de Médecine Nucléaire, Hôpital Bichat, Paris, France.

出版信息

Ann Rheum Dis. 1993 Mar;52(3):235-8. doi: 10.1136/ard.52.3.235.

DOI:10.1136/ard.52.3.235
PMID:8484680
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1005025/
Abstract

Heart disease is a rare but important complication of polymyositis. Diagnosis of myocardial disease is usually based on non-specific clinical, electrocardiographic, and echocardiographic data. This paper reports a case of polymyositis with myocardial disease diagnosed by myocardial imaging with radiolabelled antibody to myosin, a specific marker of the necrotic myocardial fibre.

摘要

心脏病是多发性肌炎一种罕见但重要的并发症。心肌病的诊断通常基于非特异性的临床、心电图和超声心动图数据。本文报告了一例通过用放射性标记的肌球蛋白抗体进行心肌成像诊断的伴有心肌病的多发性肌炎病例，肌球蛋白是坏死心肌纤维的一种特异性标志物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bfc/1005025/c33ee77e79e7/annrheumd00478-0075-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bfc/1005025/1b0793e6b422/annrheumd00478-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bfc/1005025/2c07d412e416/annrheumd00478-0074-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bfc/1005025/c33ee77e79e7/annrheumd00478-0075-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bfc/1005025/1b0793e6b422/annrheumd00478-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bfc/1005025/2c07d412e416/annrheumd00478-0074-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bfc/1005025/c33ee77e79e7/annrheumd00478-0075-a.jpg

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New application of myocardial antimyosin scintigraphy: diagnosis of myocardial disease in polymyositis.心肌抗肌凝蛋白闪烁扫描术的新应用：多肌炎中心肌疾病的诊断
Ann Rheum Dis. 1993 Mar;52(3):235-8. doi: 10.1136/ard.52.3.235.
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引用本文的文献

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111Indium antimyosin antibody imaging of primary myocardial involvement in systemic diseases.111铟抗肌凝蛋白抗体显像在系统性疾病所致原发性心肌受累中的应用
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2
Acute diffuse myocyte necrosis evidenced with 111In-antimyosin antibody scintigraphy in a patient with aortic stenosis.
J Nucl Cardiol. 1997 Sep-Oct;4(5):426-7. doi: 10.1016/s1071-3581(97)90038-6.

本文引用的文献

1
Creatine kinase MB isoenzyme in dermatomyositis: a noncardiac source.
Ann Intern Med. 1981 Mar;94(3):341-3. doi: 10.7326/0003-4819-94-3-341.
2
The heart and cardiac conduction system in polymyositis-dermatomyositis: a clinicopathologic study of 16 autopsied patients.多发性肌炎-皮肌炎中的心脏及心脏传导系统：16例尸检患者的临床病理研究
Am J Cardiol. 1982 Nov;50(5):998-1006. doi: 10.1016/0002-9149(82)90408-8.
3
Polymyositis--treatment and prognosis. A study of 107 patients.多发性肌炎——治疗与预后。对107例患者的研究。
Acta Neurol Scand. 1982 Apr;65(4):280-300. doi: 10.1111/j.1600-0404.1982.tb03087.x.
4
Myocardial injury: quantitation by cell sorting initiated with antimyosin fluorescent spheres.心肌损伤：通过抗肌球蛋白荧光微球启动的细胞分选进行定量分析。
Science. 1982 Sep 10;217(4564):1050-3. doi: 10.1126/science.7051286.
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Cardiac abnormalities in polymyositis/dermatomyositis.多发性肌炎/皮肌炎中的心脏异常。
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6
Acute myocardial infarct imaging with indium-111-labeled monoclonal antimyosin Fab.用铟 - 111标记的单克隆抗肌凝蛋白Fab片段进行急性心肌梗死显像。
J Nucl Med. 1987 Nov;28(11):1671-8.
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Indium 111-monoclonal antimyosin antibody imaging in the diagnosis of acute myocarditis.
Circulation. 1987 Aug;76(2):306-11. doi: 10.1161/01.cir.76.2.306.
8
Adult onset polymyositis/dermatomyositis: an analysis of clinical and laboratory features and survival in 76 patients with a review of the literature.成人起病的多发性肌炎/皮肌炎：76例患者的临床和实验室特征及生存情况分析并文献复习
Semin Arthritis Rheum. 1986 Feb;15(3):168-78. doi: 10.1016/0049-0172(86)90014-4.
9
Patterns of evolution of myocyte damage after human heart transplantation detected by indium-111 monoclonal antimyosin.用铟-111单克隆抗肌球蛋白检测人心脏移植后心肌细胞损伤的演变模式。
Am J Cardiol. 1988 Sep 15;62(9):623-7. doi: 10.1016/0002-9149(88)90667-4.
10
Scintigraphic quantification of myocardial necrosis in patients after intravenous injection of myosin-specific antibody.静脉注射肌球蛋白特异性抗体后患者心肌坏死的闪烁显像定量分析。
Circulation. 1986 Sep;74(3):501-8. doi: 10.1161/01.cir.74.3.501.