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童年腹股沟疝修补术所致输精管梗阻男性的血清抗精子抗体

Serum antisperm antibodies in men with vas deferens obstruction caused by childhood inguinal herniorrhaphy.

作者信息

Matsuda T, Muguruma K, Horii Y, Ogura K, Yoshida O

机构信息

Department of Urology, Kansai Medical University, Osaka, Japan.

出版信息

Fertil Steril. 1993 May;59(5):1095-7. doi: 10.1016/s0015-0282(16)55934-2.

DOI:10.1016/s0015-0282(16)55934-2
PMID:8486180
Abstract

OBJECTIVE

To study the incidence of serum antisperm antibodies in patients with vas deferens obstruction caused by childhood inguinal herniorrhaphy.

DESIGN

Retrospective.

SETTING

Kansai Medical University and Kyoto University Hospital.

PATIENTS

Thirteen patients with vas deferens obstruction caused by childhood inguinal herniorrhaphy.

MAIN OUTCOME MEASURES

Indirect immunobead test for serum antisperm antibodies.

RESULTS

Of 13 patients, 7 (54%) and 2 (15%) tested positive for immunoglobulin (Ig)G and IgA class antisperm antibodies, respectively; all patients tested negative for IgM class antibodies. The incidence of antisperm antibodies was not different between the patients with possible epididymal obstruction and those without epididymal obstruction.

CONCLUSIONS

A significant percentage of patients with vasal obstruction caused by infant inguinal herniorrhaphy have serum antisperm antibodies despite the absence of sperm granulomas.

摘要

目的

研究儿童腹股沟疝修补术所致输精管梗阻患者血清抗精子抗体的发生率。

设计

回顾性研究。

地点

关西医科大学和京都大学医院。

患者

13例因儿童腹股沟疝修补术导致输精管梗阻的患者。

主要观察指标

血清抗精子抗体的间接免疫珠试验。

结果

13例患者中,7例(54%)和2例(15%)分别检测出免疫球蛋白(Ig)G类和IgA类抗精子抗体呈阳性;所有患者IgM类抗体检测均为阴性。可能存在附睾梗阻的患者与无附睾梗阻的患者之间抗精子抗体的发生率无差异。

结论

尽管没有精子肉芽肿,但相当比例的婴儿腹股沟疝修补术所致输精管梗阻患者存在血清抗精子抗体。

相似文献

1
Serum antisperm antibodies in men with vas deferens obstruction caused by childhood inguinal herniorrhaphy.童年腹股沟疝修补术所致输精管梗阻男性的血清抗精子抗体
Fertil Steril. 1993 May;59(5):1095-7. doi: 10.1016/s0015-0282(16)55934-2.
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Quantitative analysis of testicular histology in patients with vas deferens obstruction caused by childhood inguinal herniorrhaphy: comparison to vasectomized men.儿童腹股沟疝修补术所致输精管梗阻患者睾丸组织学的定量分析:与输精管结扎男性的比较。
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Incarcerated Inguinal Hernia Mesh Repair: Effect on Testicular Blood Flow and Sperm Autoimmunity.嵌顿性腹股沟疝补片修补术:对睾丸血流和精子自身免疫的影响
Med Sci Monit. 2016 May 5;22:1524-33. doi: 10.12659/msm.898727.
2
Antisperm antibodies and testicular blood flow after inguinal hernia mesh repair.腹股沟疝修补术后的抗精子抗体与睾丸血流
Surg Endosc. 2014 Dec;28(12):3413-20. doi: 10.1007/s00464-014-3614-7. Epub 2014 Jun 25.
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Influence of inguinal hernia mesh repair on testicular flow and sperm autoimmunity.腹股沟疝网片修补术对睾丸血流和精子自身免疫的影响。
Hernia. 2012 Aug;16(4):417-24. doi: 10.1007/s10029-012-0918-1. Epub 2012 May 10.
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Physical deformities relevant to male infertility.与男性不育相关的身体畸形。
Nat Rev Urol. 2012 Feb 21;9(3):156-74. doi: 10.1038/nrurol.2012.11.