Thompson P J, Greenough A, Brooker R, Nicolaides K H, Gamsu H R
Department of Child Health, King's College Hospital, London, United Kingdom.
J Perinat Med. 1993;21(1):63-7. doi: 10.1515/jpme.1993.21.1.63.
The records of 15 cases of hydrops fetalis consecutively delivered at our institution were reviewed to determine the accuracy of antenatal diagnosis and whether antenatal diagnostic techniques yielded information useful in predicting outcome. All 15 cases were detected antenatally, five were due to rhesus haemolytic disease and 10 were non-immune hydrops. All the infants required active resuscitation. Ten infants eventually died, two had immune hydrops fetalis and 8 non-immune hydrops. Seven infants had pleural effusions, all had been detected antenatally. The presence of pleural effusions did not influence mortality. All structural abnormalities were accurately detected in those patients seen prior to labour and there were no survivors in the group of infants so affected. We conclude that the mortality of non-immune hydrops fetalis remains high and that antenatal diagnosis of this condition is accurate and provides useful prognostic information.
回顾了我院连续分娩的15例胎儿水肿病例的记录，以确定产前诊断的准确性，以及产前诊断技术是否能提供有助于预测结局的信息。所有15例均在产前被检测出，5例因恒河猴溶血病，10例为非免疫性水肿。所有婴儿均需积极复苏。10例婴儿最终死亡，2例为免疫性胎儿水肿，8例为非免疫性水肿。7例婴儿有胸腔积液，均在产前被检测出。胸腔积液的存在不影响死亡率。所有结构异常在临产前就诊的患者中均被准确检测出，且该组受影响婴儿无存活者。我们得出结论，非免疫性胎儿水肿的死亡率仍然很高，这种情况的产前诊断准确，并能提供有用的预后信息。
