Sylvestre A M, Cockshutt J R, Parent J M, Brooke J D, Holmberg D L, Partlow G D
Department of Clinical Studies, Ontario Veterinary College, Guelph.
Vet Surg. 1993 Jan-Feb;22(1):5-10. doi: 10.1111/j.1532-950x.1993.tb00360.x.
Magnetically elicited transcranial motor evoked potentials (MEPs) were studied in 37 dogs with type 1 intervertebral disc (IVD) disease. The waveforms were recorded from both cranial tibial muscles before and after surgery. The latencies and amplitudes obtained were compared to those of a control population (n = 14). MEPs were recordable in all dogs with mild or no neurologic deficits, but they were recordable in only 50% of ambulatory dogs that were severely ataxic. MEPs could not be elicited from nonambulatory dogs. There was a significant attenuation of the amplitudes in all clinical cases, even if the dogs demonstrated back pain alone. Significantly prolonged latencies were associated with neurologic deficits. MEPs were not good predictors of neurologic recovery. The responses obtained from the side where the disc material was found were not different from those recorded from the opposite side. MEPs were very sensitive to lesions of the spinal cord, as indicated by the significant changes in the waves in patients with mild or no neurologic deficits and in the loss of response in dogs that still demonstrated purposeful movement. Neurologic exams provided more accurate diagnoses and prognoses than did MEPs in dogs with IVD disease.
对37只患有1型椎间盘（IVD）疾病的犬进行了磁诱发经颅运动诱发电位（MEP）研究。在手术前后从双侧胫前肌记录波形。将获得的潜伏期和波幅与对照组（n = 14）进行比较。所有轻度或无神经功能缺损的犬均可记录到MEP，但仅50%的重度共济失调的能行走犬可记录到MEP。不能从不能行走的犬引出MEP。在所有临床病例中，即使犬仅表现为背痛，波幅也有显著衰减。显著延长的潜伏期与神经功能缺损有关。MEP不是神经功能恢复的良好预测指标。从发现椎间盘物质一侧获得的反应与从对侧记录的反应无差异。MEP对脊髓损伤非常敏感，轻度或无神经功能缺损患者波形的显著变化以及仍有目的运动的犬反应消失均表明了这一点。在患有IVD疾病的犬中，神经学检查比MEP能提供更准确的诊断和预后。
