Stahl T J, Murray J J, Coller J A, Schoetz D J, Roberts P L, Veidenheimer M C
Department of Colon and Rectal Surgery, Lahey Clinic Medical Center, Burlington, MA 01805.
Arch Surg. 1993 May;128(5):545-9; discussion 549-50. doi: 10.1001/archsurg.1993.01420170079011.
We reviewed the treatment outcome in 40 patients undergoing full-thickness local excision (seven patients) or electrocoagulation (33 patients) for adenocarcinoma of the rectum. Patients were followed up for a minimum of 5 years or until death (mean follow-up, 7.6 years). Twenty-two patients (55%) survived 5 years free of disease or were free of disease at the time of death due to other causes following local treatment. Eight (62%) of 13 patients with persistent or locally recurrent disease were successfully treated with additional local therapy, rectal resection, or combined radiation therapy and chemotherapy. Overall, 30 (75%) of 40 patients embarking on a program of local treatment for carcinoma of the rectum survived 5 years free of disease or were free of disease at the time of death due to other causes.
我们回顾了40例接受直肠腺癌全层局部切除（7例）或电凝治疗（33例）患者的治疗结果。对患者进行了至少5年的随访或直至死亡（平均随访7.6年）。22例（55%）患者存活5年无疾病复发，或在因其他原因死亡时无疾病复发，此前接受了局部治疗。13例持续性或局部复发性疾病患者中有8例（62%）通过额外的局部治疗、直肠切除术或联合放疗及化疗成功治愈。总体而言，40例接受直肠腺癌局部治疗方案的患者中有30例（75%）存活5年无疾病复发，或在因其他原因死亡时无疾病复发。
