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息肉病——腹泻的一种罕见病因。

Cap polyposis--an unusual cause of diarrhoea.

作者信息

Campbell A P, Cobb C A, Chapman R W, Kettlewell M, Hoang P, Haot B J, Jewell D P

机构信息

Nuffield Department of Pathology and Bacteriology, John Radcliffe Hospital, Oxford.

出版信息

Gut. 1993 Apr;34(4):562-4. doi: 10.1136/gut.34.4.562.

DOI:10.1136/gut.34.4.562
PMID:8491408
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1374322/
Abstract

'Cap polyposis' is a poorly recognised condition with distinct clinical, sigmoidoscopic, and pathological features that may be confused with other inflammatory conditions of the large intestine including pseudomembranous colitis and idiopathic chronic inflammatory bowel disease. The pathogenesis is unknown but on the basis of the characteristic histological appearances, which are similar to those seen in situations where mucosal prolapse is the underlying mechanism, it has been suggested that the latter may be an important aetiological factor. Two cases are described. Histological features in the first (presence of intramucosal elastin) and clinical features in the second (rectal prolapse) support the above hypothesis.

摘要

“息肉样脱垂”是一种认识不足的病症,具有独特的临床、乙状结肠镜和病理特征,可能会与包括伪膜性结肠炎和特发性慢性炎症性肠病在内的大肠其他炎症性疾病相混淆。其发病机制尚不清楚,但基于特征性的组织学表现(类似于以黏膜脱垂为潜在机制的情况所见),有人提出后者可能是一个重要的病因因素。本文描述了两例病例。第一例的组织学特征(黏膜内弹性蛋白的存在)和第二例的临床特征(直肠脱垂)支持上述假说。

相似文献

1
Cap polyposis--an unusual cause of diarrhoea.息肉病——腹泻的一种罕见病因。
Gut. 1993 Apr;34(4):562-4. doi: 10.1136/gut.34.4.562.
2
Cap polyposis occurring in the postoperative course of pelvic surgery.盆腔手术后病程中发生的帽状息肉病。
Gut. 1994 Nov;35(11):1670-2. doi: 10.1136/gut.35.11.1670.
3
Metaplastic polyps and polyposis of the colorectum.结直肠化生息肉和息肉病
Histopathology. 1980 Mar;4(2):155-70. doi: 10.1111/j.1365-2559.1980.tb02909.x.
4
Pathology of the malignant colorectal polyp.恶性大肠息肉的病理学
Hum Pathol. 1998 Jan;29(1):15-26. doi: 10.1016/s0046-8177(98)90385-9.
5
Inflammatory myoglandular polyps of the colon and rectum. A clinicopathological study of 32 pedunculated polyps, distinct from other types of polyps.结肠和直肠炎性肌腺性息肉。32例带蒂息肉的临床病理研究,与其他类型息肉不同。
Am J Surg Pathol. 1992 Aug;16(8):772-9. doi: 10.1097/00000478-199208000-00005.
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Specific histological abnormalities are more likely in biopsies of endoscopically normal large bowel after the age of 60 years.60 岁以后,内镜检查正常的大肠活检更可能出现特定的组织学异常。
Histopathology. 2012 Dec;61(6):1209-13. doi: 10.1111/j.1365-2559.2012.04317.x. Epub 2012 Aug 9.
7
[Inflammatory polyp and polyposis of colon and rectum].[结肠和直肠炎性息肉及息肉病]
Nihon Rinsho. 1994 Dec;Suppl 6:285-7.
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Cap polyposis and colitis cystica profunda: a rare association.结肠息肉病与深部囊性结肠炎:一种罕见的关联。
Histopathology. 2014 Mar;64(4):604-7. doi: 10.1111/his.12292. Epub 2013 Nov 18.
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Differential activation of total and EGF receptor (EGF-R) tyrosine kinase (tyr-k) in the rectal mucosa in patients with adenomatous polyps, ulcerative colitis and colon cancer.腺瘤性息肉、溃疡性结肠炎和结肠癌患者直肠黏膜中总表皮生长因子受体(EGF-R)酪氨酸激酶(tyr-k)的差异激活。
Hepatogastroenterology. 1997 Mar-Apr;44(14):435-40.
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[Cronkhite-Canada syndrome: a new case report].[克朗凯特-加拿大综合征:一例新病例报告]
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引用本文的文献

1
Solitary Inflammatory Cap Polyp, An Unusual Cause of Rectal Bleeding in a Pediatric Patient: A Case Report.孤立性炎性帽状息肉:小儿患者直肠出血的罕见原因——病例报告
Sage Open Pediatr. 2025 May 31;12:30502225251343136. doi: 10.1177/30502225251343136. eCollection 2025 Jan-Dec.
2
Clinical, endoscopic, pathological characteristics and management of cap polyposis: experience from a Tertiary Hospital in China.结肠息肉病的临床、内镜、病理特征及处理:来自中国一家三级医院的经验
Front Pharmacol. 2024 May 9;15:1391367. doi: 10.3389/fphar.2024.1391367. eCollection 2024.
3
Cap Polyposis: An Elusive Diagnosis in a Pediatric Patient Successfully Managed With Endoscopic Treatment.

本文引用的文献

1
Mucosal prolapse syndrome--a unifying concept for solitary ulcer syndrome and related disorders.黏膜脱垂综合征——孤立性溃疡综合征及相关疾病的统一概念。
J Clin Pathol. 1983 Nov;36(11):1264-8. doi: 10.1136/jcp.36.11.1264.
2
'Diamond-shaped' crypts and mucosal elastin: helpful diagnostic features in biopsies of rectal prolapse.“菱形”隐窝与黏膜弹性蛋白:直肠脱垂活检中的有用诊断特征
Histopathology. 1990 Aug;17(2):129-34. doi: 10.1111/j.1365-2559.1990.tb00683.x.
3
Pathological mimics of chronic inflammatory bowel disease.慢性炎症性肠病的病理模仿物
息肉病:一名儿科患者的疑难诊断,经内镜治疗成功处理
ACG Case Rep J. 2022 Dec 7;9(12):e00918. doi: 10.14309/crj.0000000000000918. eCollection 2022 Dec.
4
Solitary rectal ulcer transformation to cap polyposis in a 15-year-old child.15 岁儿童孤立性直肠溃疡转化为帽状息肉。
BMC Gastroenterol. 2022 Mar 7;22(1):104. doi: 10.1186/s12876-022-02122-2.
5
BRAF Mutation Is Associated with Hyperplastic Polyp-Associated Gastric Cancer.BRAF 突变与增生性息肉相关的胃癌相关。
Int J Mol Sci. 2021 Nov 25;22(23):12724. doi: 10.3390/ijms222312724.
6
Cap polyposis in children: case report and literature review.儿童结直肠息肉病:病例报告与文献综述
Int J Colorectal Dis. 2019 Feb;34(2):363-368. doi: 10.1007/s00384-018-3192-6. Epub 2018 Nov 13.
7
Polypectomy for Recurrent Inflammatory Cap Polyposis Combined with Argon Plasma Coagulation.复发性炎性帽状息肉病的息肉切除术联合氩离子凝固术
ACG Case Rep J. 2018 May 9;5:e35. doi: 10.14309/crj.2018.35. eCollection 2018.
8
Cap polyposis refractory to eradication treated with endoscopic submucosal dissection.经内镜黏膜下剥离术治疗后难以根除的息肉病。
World J Gastrointest Endosc. 2017 Oct 16;9(10):529-534. doi: 10.4253/wjge.v9.i10.529.
9
Exploring the role and diversity of mucins in health and disease with special insight into non-communicable diseases.探索黏蛋白在健康与疾病中的作用及多样性,特别深入了解非传染性疾病。
Glycoconj J. 2015 Nov;32(8):575-613. doi: 10.1007/s10719-015-9606-6. Epub 2015 Aug 4.
10
A patient experiencing bloody diarrhea and tenesmus for three weeks.一名患者出现血性腹泻和里急后重症状三周。
Intest Res. 2015 Apr;13(2):180-1. doi: 10.5217/ir.2015.13.2.180. Epub 2015 Apr 27.
J Clin Pathol. 1991 Sep;44(9):726-33. doi: 10.1136/jcp.44.9.726.