Campbell A P, Cobb C A, Chapman R W, Kettlewell M, Hoang P, Haot B J, Jewell D P
Nuffield Department of Pathology and Bacteriology, John Radcliffe Hospital, Oxford.
Gut. 1993 Apr;34(4):562-4. doi: 10.1136/gut.34.4.562.
'Cap polyposis' is a poorly recognised condition with distinct clinical, sigmoidoscopic, and pathological features that may be confused with other inflammatory conditions of the large intestine including pseudomembranous colitis and idiopathic chronic inflammatory bowel disease. The pathogenesis is unknown but on the basis of the characteristic histological appearances, which are similar to those seen in situations where mucosal prolapse is the underlying mechanism, it has been suggested that the latter may be an important aetiological factor. Two cases are described. Histological features in the first (presence of intramucosal elastin) and clinical features in the second (rectal prolapse) support the above hypothesis.
“息肉样脱垂”是一种认识不足的病症,具有独特的临床、乙状结肠镜和病理特征,可能会与包括伪膜性结肠炎和特发性慢性炎症性肠病在内的大肠其他炎症性疾病相混淆。其发病机制尚不清楚,但基于特征性的组织学表现(类似于以黏膜脱垂为潜在机制的情况所见),有人提出后者可能是一个重要的病因因素。本文描述了两例病例。第一例的组织学特征(黏膜内弹性蛋白的存在)和第二例的临床特征(直肠脱垂)支持上述假说。