Larner J M, Malcolm R H, Mills S E, Frierson H F, Banks E R, Levine P A
Division of Therapeutic Radiology and Oncology, University of Virginia Health Sciences Center, Charlottesville 22908.
Head Neck. 1993 May-Jun;15(3):249-52. doi: 10.1002/hed.2880150314.
Basaloid squamous cell carcinoma (BSCC) of the head and neck is a recently described high-grade variant of squamous cell carcinoma. It is a biologically virulent neoplasm with a propensity for nodal, as well as systemic, metastases. Because of the limited number of published reports, we reviewed data from patients of the University of Virginia Health Sciences Center and identified 16 cases of BSCC. The intent of this study was to determine the role of radiotherapy in the treatment of BSCC and better define the clinical features of this entity. Radiotherapy alone, or in combination with surgery, resulted in excellent local control rates. Distant metastases, chiefly pulmonary, occurred in more than half of the patients.
头颈部基底样鳞状细胞癌（BSCC）是一种最近才被描述的高级别鳞状细胞癌变体。它是一种具有生物侵袭性的肿瘤，易于发生淋巴结转移以及全身转移。由于已发表的报告数量有限，我们回顾了弗吉尼亚大学健康科学中心患者的数据，确定了16例BSCC病例。本研究的目的是确定放射治疗在BSCC治疗中的作用，并更好地界定该实体的临床特征。单独放疗或放疗联合手术均取得了出色的局部控制率。超过半数的患者发生了远处转移，主要是肺转移。
